DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1271 and Kat60

DIOPT Version :9

Sequence 1:	NP_647763.1	Gene:	CG1271 / 38364	FlyBaseID:	FBgn0035392	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	44/248 - (17%)
Similarity:	89/248 - (35%)	Gaps:	74/248 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GPPDSPAFILALDVGTTCVRSFV--------------------------------------LDEQ 51
            |||.:...:||..|.|.|..:|.                                      :|..
  Fly   366 GPPGTGKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTIFIDEIDSL 430

  Fly    52 CEVRGSAVD-------AVELLNPQPGYFEIEPESLWRKIVGVITQAVKNAQLTPPDI-TCLTIST 108
            |..|||..:       ..|||....|....|.::   |:|.|:.     |...|.|| ..|....
  Fly   431 CSRRGSESEHEASRRVKSELLVQMDGVGGGEEQA---KVVMVLA-----ATNFPWDIDEALRRRL 487

  Fly   109 QRCTFLTWDHRSGEYYHNFITWKDLRADELVDQWNASWTKSSMNWFSYA-LFLLTRQSRFLAGSV 172
            ::..::......|......|..::::.|:.||   .::..:.:..:|.| :..:.|::..:  |:
  Fly   488 EKRIYIPLPSDEGREALLKINLREVKVDDSVD---LTYVANELKGYSGADITNVCREASMM--SM 547

  Fly   173 LQLMNGQVTPRLLFEI--------MNNKKLKQALMQ-----KKARVELLDSWI 212
            .:.:.| :||..:.::        ::||...:|:.:     .:|.::..:.|:
  Fly   548 RRKIAG-LTPEQIRQLATEEVDLPVSNKDFNEAMSRCNKSVSRADLDKYEKWM 599

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1271	NP_647763.1	GlpK	32..555	CDD:223628	41/241 (17%)
CG1271	NP_647763.1	FGGY_GK5_metazoa	32..552	CDD:212665	41/241 (17%)
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	6/14 (43%)
		AAA	358..496	CDD:214640	27/137 (20%)
		AAA	362..495	CDD:278434	27/136 (20%)
		Vps4_C	<570..603	CDD:286426	5/30 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900