DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1271 and Gk2

DIOPT Version :9

Sequence 1:	NP_647763.1	Gene:	CG1271 / 38364	FlyBaseID:	FBgn0035392	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001286904.1	Gene:	Gk2 / 38221	FlyBaseID:	FBgn0035266	Length:	576	Species:	Drosophila melanogaster

Alignment Length:	550	Identity:	147/550 - (26%)
Similarity:	241/550 - (43%)	Gaps:	82/550 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LDVGTTCVRSFVLDEQCEVRGSAVDAVEL--LNPQPGYFEIEPESLWRKIVGVITQAVKNAQ--- 95
            :|.||..: .|.:....:.:..|...|||  :.||.|::|.:|..:...|.....:|:|...
  Fly    36 IDEGTKTI-GFSIYTTPDFKEIAAHRVELSVITPQDGWYEQDPLEMMASINKCAEEAIKQLPEQG 99

  Fly    96 LTPPDITCLTISTQRCTFLTWDHRSGEYYHNFITWKDLRADELVDQWNASWTKSSMNWFSYALFL 160
            .:..||..:.|:.||.|.:.||..:|:..:|.:.|||:|....|:|..|.  ....|.|
  Fly   100 FSASDIVTVGITNQRETTIVWDAVTGKPLYNALLWKDIRTSTTVEQIVAK--VQDPNHF------ 156

  Fly   161 LTRQSRFLAGSVLQLMNGQVTPRLLFEIMNNKKLKQALMQKKARVELLDSWILHKLRTGSSRDKD 225
                 |...|..:......:..|.|.:  |..:::||:.:::.:...:||||:..|..|:.
  Fly   157 -----RSSTGLPISTYFSALKIRWLRD--NVPEVRQAIRERRCKAGTVDSWIVWNLTNGAL---- 210

  Fly   226 VEHITDVTSSTATGLYDPFTLSWSPLISWLFGINSKILPRVVDNGYKGFGHVHPTAFGPDWANTE 290
              ||||||:::.|.|.:..|.:|.|::...|||..::||.:         |.....||...:...
  Fly   211 --HITDVTNASRTLLMNLETQAWDPVLLKTFGIREEMLPTI---------HSCSEIFGKITSERS 264

  Fly   291 ----IPIAASLSDQTAAIWGSQCFQKNDVKVTMGTGAFLNLVTGDRCQAVISGMYPLVAWQF--K 349
                :.::..:.:|.|::.|..|.:....|.|..:|.||...|||:......|:...||::.  :
  Fly   265 PLRGMTLSGIMGNQQASLLGQMCVKPGQTKNTYRSGCFLLCNTGDKPVFSRHGLLTTVAYKLGPQ 329

  Fly   350 KPTRQQGAVYCIEGASHDFGTVVTWAQS-CELFDSPANTSDIAQSVPDTNDVFFMPAFSGLGPPV 413
            .||     :|.||||....|..::|.|: ..:.....:....|:.||.:.||:|:|||:||..|.
  Fly   330 APT-----IYAIEGAVSVAGHALSWLQNKVRILPDSRDAEKYAEMVPTSGDVYFVPAFTGLYAPY 389

  Fly   414 NDYRSASGFIGLTPSTTKAHMVRALLESIVFRLVQLIEAAEKETSQKLHMIRVDGGVSRNDFVCQ 478
            ....:....||||..|.|.|:|||.||||.|:...::|...:|...:::.:..||.::.|:.:.|
  Fly   390 WRQNARGIIIGLTQFTRKNHIVRAALESICFQTRDILECMHQECGYEINKLHADGKLTTNNLLMQ 454

  Fly   479 FLADLSRLRVERADNAESSIMGATFMA----GINLGIWRDVNDLKRFRKVARVFEPRPKEYETI- 538
            ..||...:.|.|:...:|:..||...|    |:||                ..|||..:.||.:
  Fly   455 LQADTIGMPVFRSQLMDSTAFGAAMCAAQADGVNL----------------CQFEPEKRYYENVH 503

  Fly   539 -------------ANRMDKWSRTIARFSDW 555
                         ..|..||.|.:.|...|
  Fly   504 YDTFLATTTDVERKERYGKWKRAVERSLGW 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1271	NP_647763.1	GlpK	32..555	CDD:223628	146/548 (27%)
CG1271	NP_647763.1	FGGY_GK5_metazoa	32..552	CDD:212665	145/545 (27%)
Gk2	NP_001286904.1	glycerol_kin	31..533	CDD:273549	146/548 (27%)
Gk2	NP_001286904.1	FGGY_GK1-3_metazoa	31..533	CDD:212664	146/548 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352321at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10196
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850