DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1271 and KATNA1

DIOPT Version :9

Sequence 1:NP_647763.1 Gene:CG1271 / 38364 FlyBaseID:FBgn0035392 Length:556 Species:Drosophila melanogaster
Sequence 2:NP_008975.1 Gene:KATNA1 / 11104 HGNCID:6216 Length:491 Species:Homo sapiens


Alignment Length:209 Identity:44/209 - (21%)
Similarity:73/209 - (34%) Gaps:79/209 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   380 LFDSPANTSD--IAQSV-PDTNDVFFMPAFSGLGPPVNDYRSASGFIGLTPSTTKAHMVRALLES 441
            |...|..|..  :|::| .:....||..:.|.|   .:.||..|           ..:||.|.|.
Human   246 LMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL---TSKYRGES-----------EKLVRLLFEM 296

  Fly   442 IVFRLVQLI-------------EAAEKETSQKLH---MIRVD--GGVSRNDFVCQFLADLSRLRV 488
            ..|.....|             .:.|.|.|:::.   ::::|  ||.|.||       |.|::.:
Human   297 ARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGTSEND-------DPSKMVM 354

  Fly   489 ERADNAESSIMGATFMAGINLGIWRDVNDLKRFRKVARVFEPRP-------------KEYE---- 536
                     ::.||...      | |:::..|.|...|::.|.|             :|.|    
Human   355 ---------VLAATNFP------W-DIDEALRRRLEKRIYIPLPSAKGREELLRISLRELELADD 403

  Fly   537 ----TIANRMDKWS 546
                :||..|:.:|
Human   404 VDLASIAENMEGYS 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1271NP_647763.1 GlpK 32..555 CDD:223628 44/209 (21%)
FGGY_GK5_metazoa 32..552 CDD:212665 44/209 (21%)
KATNA1NP_008975.1 Interaction with microtubules 1..185
Interaction with dynein and NDEL1. /evidence=ECO:0000250 1..75
Interaction with KATNB1. /evidence=ECO:0000269|PubMed:10751153 1..29
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 87..185
AAA 241..382 CDD:214640 37/172 (22%)
AAA 245..381 CDD:278434 36/171 (21%)
Vps4_C <456..489 CDD:286426
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0554
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.