DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1271 and gk5

DIOPT Version :9

Sequence 1:	NP_647763.1	Gene:	CG1271 / 38364	FlyBaseID:	FBgn0035392	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	XP_004917888.1	Gene:	gk5 / 101734558	XenbaseID:	XB-GENE-983229	Length:	561	Species:	Xenopus tropicalis

Alignment Length:	527	Identity:	204/527 - (38%)
Similarity:	321/527 - (60%)	Gaps:	24/527 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ILALDVGTTCVRSFVLDEQCEVRGSAVDAVELLNPQPGYFEIEPESLWRKIVGVITQAVKNAQLT 97
            |:|:|||::.:|..:.::..::.|||.|.:::|.||.||.||:|||||.:.||::.:|:|:|.:.
Frog    13 IVAVDVGSSVLRCHLYNQAGQICGSAEDKLKVLYPQTGYVEIDPESLWDQFVGIVKEAIKDAGIQ 77

  Fly    98 PPDITCLTISTQRCTFLTWDHRSGEYYHNFITWKDLRADELVDQWNASWTKSSMNWFSYALFLLT 162
            ...:..|.|||||.||:||:..:||.:||||:|:||||.:||..||:|....:::....||...|
Frog    78 MSQVAGLGISTQRATFITWNKTTGEPFHNFISWQDLRAADLVSSWNSSVLLKAVHGVCTALHFFT 142

  Fly   163 RQSRFLAGSVLQLMNGQVTPRLLFEIMNNKKLKQALMQKKARVELLDSWILHKLRTGSSRDKDVE 227
            |:.||||.|::......|:.||::.:.|..:::|...........:|:|:|:||.:|:      .
Frog   143 RRKRFLAASLINFTTQHVSLRLVWVLQNIPQVRQEAKIGNCCFGTIDTWLLYKLTSGT------V 201

  Fly   228 HITDVTSSTATGLYDPFTLSWSPLISWLFGINSKILPRVVDNGYKGFGHVHPTAFGPDWANTEIP 292
            ..||.::::.|.::||:.:.||..:..|..|...|.|.|.|..: .||...|..||     ..:|
Frog   202 FATDYSNASGTAIFDPYLMCWSSFLCSLLSIPMSIFPSVEDTSH-NFGLADPIIFG-----AAVP 260

  Fly   293 IAASLSDQTAAIWGSQCFQKNDVKVTMGTGAFLNLVTGDRCQAVISGMYPLVAWQFKKPTRQQGA 357
            |.|.::||.||::|..||...:||:|||||:|:::.||:|....|:|:|||:.|:..|      .
Frog   261 IRALVADQQAAMFGQCCFDVGNVKLTMGTGSFISINTGERLHTSIAGLYPLIGWKIGK------E 319

  Fly   358 VYCI-EGASHDFGTVVTWAQSCELFDSPANTSDIAQSVPDTNDVFFMPAFSGLGPPVNDYRSASG 421
            |.|: ||.:.|.||.:.||:...||.|.|:|..:|:||||...::|:|:||||..||||..:.:.
Frog   320 VVCLAEGNASDTGTAIKWAEELNLFTSVADTEAMARSVPDCGGIYFVPSFSGLQAPVNDPYACAS 384

  Fly   422 FIGLTPSTTKAHMVRALLESIVFRLVQLIEAAEKETSQKLHMIRVDGGVSRNDFVCQFLADLSRL 486
            |:||.|||:|.|:|||:|||:.:|..||.:...:||:..:.:||.|||||.|:|:.|..|||...
Frog   385 FMGLKPSTSKNHLVRAILESVAYRNKQLYDTVLRETTIPITLIRADGGVSNNNFIMQMTADLLGQ 449

  Fly   487 RVERADNAESSIMGATFMAGINLGIWRDVNDLKRFRKVARVFEPRP--KEYETIANRMDKWSRTI 549
            .:::..:.:.|.:||.|:||:.:|:|...::||:.|.....|||:.  ||||   ..|..|...:
Frog   450 TIDKPKHTDMSSLGAAFLAGLAVGLWSTKDELKKLRTTQCEFEPQAKWKEYE---QSMGSWEVAL 511

  Fly   550 ARFSDWY 556
            .|.|:||
Frog   512 QRCSNWY 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1271	NP_647763.1	GlpK	32..555	CDD:223628	202/524 (39%)
CG1271	NP_647763.1	FGGY_GK5_metazoa	32..552	CDD:212665	200/521 (38%)
gk5	XP_004917888.1	FGGY_GK5_metazoa	13..514	CDD:212665	200/521 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	160	1.000	Domainoid score	I4017
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H15141
Inparanoid	1	1.050	380	1.000	Inparanoid score	I2016
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352321at33208
OrthoFinder	1	1.000	-	-		FOG0006572
OrthoInspector	1	1.000	-	-		oto105522
Panther	1	1.100	-	-	LDO	PTHR10196
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5572
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160