DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1271 and gk

DIOPT Version :9

Sequence 1:	NP_647763.1	Gene:	CG1271 / 38364	FlyBaseID:	FBgn0035392	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	XP_012811696.1	Gene:	gk / 100038285	XenbaseID:	XB-GENE-961541	Length:	562	Species:	Xenopus tropicalis

Alignment Length:	542	Identity:	154/542 - (28%)
Similarity:	253/542 - (46%)	Gaps:	57/542 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 ALDVGTTCVRSFVLDEQCEVRGSAVDAVELLN----------PQPGYFEIEPESLWRKIVGVITQ 89
            |:|.||:..|..|.:.:         ..|||:          |:.|:.|.:|:.:.:.:...:.:
Frog    15 AIDQGTSSTRFLVFNAK---------TAELLSHHQVEIKQKFPKEGWVEQDPKEILQSVYECVEK 70

  Fly    90 AVKNAQLTPPDIT---CLTISTQRCTFLTWDHRSGEYYHNFITWKDLRADELVDQWNASWTKSSM 151
            ..:.......|||   .:.:|.||.|.:.||..:||..:|.:.|.|||....|::........:.
Frog    71 TCEKLTQLNIDITNIKAIGVSNQRETTVVWDKTTGEPLYNAVVWLDLRTQSTVERLLKRIPGKNK 135

  Fly   152 NWFSYALFLLTRQSRFLAGSVLQLMNGQVTPRLLFEIMNNKKLKQALMQKKARVELLDSWILHKL 216
            |:|         :||  .|..|......|..|.|.:  |.::::.|:.:.:|....:||||:..|
Frog   136 NFF---------KSR--TGLPLSTYFSAVKIRWLLD--NVEEIRHAVSEGRAMFGTVDSWIIWSL 187

  Fly   217 RTGSSRDKDVEHITDVTSSTATGLYDPFTLSWSPLISWLFGINSKILPRVVDNG-YKGFGHVHPT 280
             ||:....  .|.||||:::.|.|::..||.|...:...|.|..::||:|..:. ..|...:.|:
Frog   188 -TGAKNGG--VHCTDVTNASRTMLFNIHTLEWDTELCQFFDIPMELLPKVRSSSEIYGLMKICPS 249

  Fly   281 AFGPDWANTEIPIAASLSDQTAAIWGSQCFQKNDVKVTMGTGAFLNLVTGDRCQAVISGMYPLVA 345
            .  ...|.|.:||:..|.||:||:.|..|||....|.|.|||.||...||.:......|:...||
Frog   250 L--KSGALTGVPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGSKPVLSEHGLLTTVA 312

  Fly   346 WQFKKPTRQQGAVYCIEGASHDFGTVVTWAQ-SCELFDSPANTSDIAQSVPDTNDVFFMPAFSGL 409
            :   |..|.:.|.|.:||:....|.||.|.: :..:..:......:|..|..:...:|:||||||
Frog   313 Y---KLGRDKPACYALEGSVAIAGAVVRWLRDNLGIVKTTEEVEKLAAEVGTSYGCYFVPAFSGL 374

  Fly   410 GPPVNDYRSASGFI-GLTPSTTKAHMVRALLESIVFRLVQLIEAAEKETSQKLHMIRVDGGVSRN 473
            ..|..: .||.|.| |||..|.:.|:..|.||::.|:..::::|..|:....|:.::||||::.|
Frog   375 YAPYWE-PSARGIICGLTQFTNRNHIAFAALEAVCFQTREILDAMNKDCGIPLNQLQVDGGMTSN 438

  Fly   474 DFVCQFLADLSRLRVERADNAESSIMGATFMAGI--NLGIWR-DVNDLKRFRKVARVFEPR--PK 533
            ..:.|..||:..:.|.:....|::.:||...||.  .:|:|. :..||...  ....|||:  |:
Frog   439 KILMQLQADILCIPVVKPSMPETTALGAAMAAGAAEGVGVWSLNPGDLTAV--TCERFEPQINPE 501

  Fly   534 EYETIANRMDKWSRTIARFSDW 555
            |.|.   |..:|.:.:.:...|
Frog   502 ESEF---RYARWKKAVMKSMGW 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1271	NP_647763.1	GlpK	32..555	CDD:223628	153/540 (28%)
CG1271	NP_647763.1	FGGY_GK5_metazoa	32..552	CDD:212665	153/537 (28%)
gk	XP_012811696.1	FGGY_GK1-3_metazoa	11..520	CDD:212664	153/540 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352321at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920