DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32485 and Sec14l2

DIOPT Version :9

Sequence 1:	NP_728794.1	Gene:	CG32485 / 38363	FlyBaseID:	FBgn0052485	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_653103.1	Gene:	Sec14l2 / 67815	MGIID:	1915065	Length:	403	Species:	Mus musculus

Alignment Length:	237	Identity:	49/237 - (20%)
Similarity:	108/237 - (45%)	Gaps:	23/237 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ELAPINEQDFKDLKERMKLIVEADPKQYHNDFSLRRYLRAFKTTDDAFQAILKTN-KWRETYGVD 68
            :|:|..|:.....:|.::.::...|..  :|:.|.|:|||........:|:|:.: ::|:...:|
Mouse     7 DLSPKQEEALAKFRENVQDVLPTLPNP--DDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDID 69

  Fly    69 KLSEMDRSQLDKKARLLRHR---DCIGRPVIY-----IPAKNHSSERDIDELTRFIVYNLEEACK 125
            |:......::.:: .|...|   |..|.||.|     :.||.........:|.|..:.:.|...:
Mouse    70 KIISWQPPEVIQQ-YLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLLQ 133

  Fly   126 KCFEEVT------DRLCIVFDLAEFSTSCMDYQLVQ---NLIWLLGKHFPERLGVCLIINSPGLF 181
            :|.::.|      :.:.:::|........:....|:   ..:.:..:::||.|....::.:|.||
Mouse   134 ECIQQTTKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLF 198

  Fly   182 STIWPAIRVLLDDNTAKKVKFV-ADEAE-LCQYLIPDILPTD 221
            ...:..|:..|.::|.:|:..: |:..| |.:::.||.||.:
Mouse   199 PVAYNLIKPFLSEDTRRKIMVLGANWKEVLLKHISPDQLPVE 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32485	NP_728794.1	CRAL_TRIO	85..219	CDD:279044	30/152 (20%)
Sec14l2	NP_653103.1	CRAL_TRIO_N	13..59	CDD:215024	11/47 (23%)
		SEC14	76..244	CDD:214706	33/166 (20%)
		GOLD_2	300..381	CDD:290608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133487at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820