DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32485 and CLVS1

DIOPT Version :9

Sequence 1:	NP_728794.1	Gene:	CG32485 / 38363	FlyBaseID:	FBgn0052485	Length:	222	Species:	Drosophila melanogaster
Sequence 2:	NP_775790.1	Gene:	CLVS1 / 157807	HGNCID:	23139	Length:	354	Species:	Homo sapiens

Alignment Length:	237	Identity:	52/237 - (21%)
Similarity:	99/237 - (41%)	Gaps:	36/237 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ERMKLIVEADPKQYHNDFS---------------------LRRYLRAFKTTD-DAFQAILKTNKW 61
            |:.:|.:..:|...|.|..                     :.|:|||.|... |||:.:.:..::
Human    36 EKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQY 100

  Fly    62 RETYGVDKLSE-------MDRSQLDKKARLLRHRDCIGRPVIYIPAKNHSSERD-IDELTRFIVY 118
            |: ..:|....       :.|:.:|....:|.:||..||.::.:.|.|....|: ..::.|.|:.
Human   101 RQ-LNLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILL 164

  Fly   119 NLEEACKKCFEEVTDRLCIVFDLAEFS---TSCMDYQLVQNLIWLLGKHFPERLGVCLIINSPGL 180
            :||...:....::...:.|: |.:.||   .|.:...:::..|..|...||.|.|....:|.|..
Human   165 SLEVLIEDPELQINGFILII-DWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWY 228

  Fly   181 FSTIWPAIRVLLDDNTAKKVKFVADEA-ELCQYLIPDILPTD 221
            ...::..|:..|.|.|.|::....:.. .|.|.:.|:.||::
Human   229 IHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32485	NP_728794.1	CRAL_TRIO	85..219	CDD:279044	33/138 (24%)
CLVS1	NP_775790.1	CRAL_TRIO_N	51..97	CDD:215024	9/45 (20%)
		CRAL_TRIO	125..274	CDD:306996	35/147 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	333..354
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810