DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scramb2 and AIM25

DIOPT Version :9

Sequence 1:	NP_647761.1	Gene:	scramb2 / 38362	FlyBaseID:	FBgn0035390	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_012634.3	Gene:	AIM25 / 853563	SGDID:	S000003861	Length:	327	Species:	Saccharomyces cerevisiae

Alignment Length:	254	Identity:	56/254 - (22%)
Similarity:	103/254 - (40%)	Gaps:	66/254 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 TALDQ--LLVSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGR----SRPFE 117
            |.|::  :::.::||.:.:..|||..||:.:.:..|..:....|.....|:.::.:    .|||.
Yeast    74 TILNEPTVIIERQIEFMNVFLGFEQANRYAIMDVNGNKIASMMERDFSITKAIMRQFYRLHRPFL 138

  Fly   118 MKILDNFQNEVLHLYRPFKCDILCCFPSCMNA-VEVSAPP------------------GQVIGSV 163
            :.:.||:.|.::.:.|||         |.:|: ::...||                  |..:|..
Yeast   139 VDVFDNWGNVIMTIKRPF---------SFINSHIKTIIPPSAYVDNGSDSTHYHDGKEGTTVGET 194

  Fly   164 EQVCTFMRPKF------NIKNTCGDTVLQIEGPVCPCKCFSDTNFKVLSANNEEIGKISKQWSGL 222
            .|.....|.::      .::.:..|...:|:.|      |...:|.|..|:.:.:..:.:.|.||
Yeast   195 IQNWHLWRRRYELFQKDGVEGSTFDQFGKIDAP------FLSFDFPVTDADGKIMASVDRNWVGL 253

  Fly   223 GRELFTDADYFSVTFP------------------LNLDVRMKALIFAALFLIDAVYYEQ 263
            |||:|||...:.|.|.                  |.||.|  |::.|....||..|:.:
Yeast   254 GREMFTDTGVYVVRFDSQRCFDNIYPTEMLSSQVLTLDQR--AVLLANAVSIDFDYFSR 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	56/252 (22%)
AIM25	NP_012634.3	Scramblase	59..310	CDD:252175	56/252 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I2483
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I1798
Isobase	1	0.950	-	0	Normalized mean entropy	S1940
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100156
Panther	1	1.100	-	-	O	PTHR23248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
TreeFam	1	0.960	-	-
	11	10.770