Protein Alignment scramb2 and PLSCR1

DIOPT Version :10

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001392962.1
• Gene: PLSCR1 / 5359
• HGNCID: 9092
• Length: 330
• Species: Homo sapiens
• Alignment Length: 161
• Identity: 36/161 - (22%)
• Similarity: 53/161 - (32%)
• Gaps: 60/161 - (37%)

  Fly    32 LKVSAEIKR----RSHSSSPKRP--SRRNSGEGT-----PLWRKTGAASFRHASPLRKESHSKDG 85
            |::.:|::|    .|....|..|  |...|..|:     |:.|..|..||:. .||..
Human    62 LELRSELRRERGTESRLGGPGAPGTSGTLSSPGSLDPVGPITRHLGQPSFQQ-QPLEP------- 118

  Fly    86 VAGGGDGPSAGKFTDKQYLNILQSMAQAVHVFDLNGQIIFWNSMAEKLYGFSAAEALGKDSINIL 150
                |:.|......|:..:.:|.               .|:..  ||.|.
Human   119 ----GEDPLPPDSQDRHQMALLN---------------FFFPD--EKAYS--------------- 147

  Fly   151 VDGQDAAVAKNIFQRCSSGESWTGEFPVKNK 181
             :.:...|.:|  :|..|||...|  |||||
Human   148 -EEESRRVRRN--KRSKSGEGADG--PVKNK 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	33/147 (22%)
PLSCR1	NP_001392962.1	PHA03378	<34..>109	CDD:223065	12/46 (26%)
		Scramblase	98..319	CDD:252175	27/125 (22%)