Protein Alignment scramb2 and Plscr3

DIOPT Version :10

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001012139.1
• Gene: Plscr3 / 360549
• RGDID: 1307016
• Length: 296
• Species: Rattus norvegicus
• Alignment Length: 259
• Identity: 106/259 - (40%)
• Similarity: 147/259 - (56%)
• Gaps: 13/259 - (5%)

  Fly    11 PQNAPQDENG-----AVVLQPQAANVGNNANGPENWMSIPVGMPNCPQGLEYLTALDQLLVSQKI 70
            |..||....|     ...|.|....|.....||.      |.:|..|.|||:|..:||:|:.||.
  Rat    34 PGQAPVPTQGPAPAPGFSLFPSPGPVVPGPPGPF------VPLPGVPSGLEFLVQIDQILIHQKA 92

  Fly    71 EKLELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILDNFQNEVLHLYRPF 135
            |::|...|:||.||:::::..||.:..|.|||:||.|...|..||..:::.|....|||.|.||.
  Rat    93 ERVETFLGWETCNRYELRSGTGQQLGQAAEESNCCARLCCGARRPLRIRLADPGDREVLRLLRPL 157

  Fly   136 KCDILCCFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVCPCKCFSDT 200
            .|...|| |..:..:||.||||..||.|.|......|||:|.:.....||::.||.|.|.|.:||
  Rat   158 HCGCSCC-PCGLQEMEVQAPPGTTIGHVLQTWHPFIPKFSILDADRQPVLRVVGPCCTCGCGTDT 221

  Fly   201 NFKVLSAN-NEEIGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFAALFLIDAVYYEQ 263
            ||:|.:.: :..:|:|||||.||.||..||||.|.:.||::||||:||::..|.||||.:::|:
  Rat   222 NFEVKTKDESRSVGRISKQWGGLLREALTDADDFGLQFPVDLDVRVKAVLLGATFLIDYMFFEK 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	96/221 (43%)
Plscr3	NP_001012139.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		6/23 (26%)
		Proline-rich domain (PRD). /evidence=ECO:0000250|UniProtKB:O15162	1..58		6/23 (26%)
		SH3-binding 1. /evidence=ECO:0000255	7..15
		PPxY motif. /evidence=ECO:0000255	15..18
		SH3-binding 2. /evidence=ECO:0000255	21..27
		SH3-binding 3. /evidence=ECO:0000255	66..71		2/10 (20%)
		Scramblase	73..285	CDD:252175	94/212 (44%)