Protein Alignment scramb2 and Plscr4

DIOPT Version :10

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_848826.1
• Gene: Plscr4 / 235527
• MGIID: 2143267
• Length: 326
• Species: Mus musculus
• Alignment Length: 256
• Identity: 98/256 - (38%)
• Similarity: 145/256 - (56%)
• Gaps: 4/256 - (1%)

  Fly    10 LPQNAPQDENGAVVLQPQAANVGNNANGPENWMSIPVGMPNCPQGLEYLTALDQLLVSQKIEKLE 74
            :|...|......:..||....| .|...|..||:.|..:||||.|||||..||.:.|.|.:|.||
Mouse    65 IPLYHPTGGTHPIQYQPGKYPV-TNQPAPIMWMAGPAPVPNCPPGLEYLAQLDNIHVLQHVEPLE 128

  Fly    75 LLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILDNFQNEVLHLYRPFKCDI 139
            |:|.|||.||:.:||::.|.||...|::|..|||.....|||.:::.|....|::.:.|||:|..
Mouse   129 LMTRFETNNRYDIKNNIDQMVYIVTEDTDDFTRNAYRNLRPFVLRVTDCLGREIMTMQRPFRCTC 193

  Fly   140 LC-CFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVCPCKCFSDTNFK 203
            .| |.|.....:||..|||..||.|.:.....|..::|:|...::::::.||.....|.||:.|:
Mouse   194 CCFCCPCARQELEVQCPPGVTIGFVAEHWNLCRASYSIQNEKKESMMRVRGPCATYGCGSDSVFE 258

  Fly   204 VLSANN-EEIGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFAALFLIDAVYYEQ 263
            :.|.:. ..||.|.::|:|. .....:||:|.:.|||.|||:|||:||.:.||||.:|:|:
Mouse   259 INSLDGVSNIGSIIRKWNGF-LSTMVNADHFEIRFPLALDVKMKAMIFGSCFLIDFMYFER 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	89/222 (40%)
Plscr4	NP_848826.1	Proline-rich domain (PRD). /evidence=ECO:0000250|UniProtKB:O15162	1..94		7/29 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32
		SH3-binding 1. /evidence=ECO:0000255	18..25
		PPxY motif. /evidence=ECO:0000255	30..33
		SH3-binding 2. /evidence=ECO:0000255	41..49
		SH3-binding 3. /evidence=ECO:0000255	94..102		3/7 (43%)
		Scramblase	96..318	CDD:252175	89/222 (40%)