Protein Alignment scramb2 and scrm-2

DIOPT Version :9

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_493321.1
• Gene: scrm-2 / 191509
• WormBaseID: WBGene00014200
• Length: 265
• Species: Caenorhabditis elegans
• Alignment Length: 260
• Identity: 97/260 - (37%)
• Similarity: 143/260 - (55%)
• Gaps: 14/260 - (5%)

  Fly    13 NAPQD----ENGAVVLQPQAANVGNNANGPENWMSIPVGMPNCPQGLEYLTALDQLLVSQKIEKL 73
            |.|.|    |:.|:..:|.|:   ..|.....||.....:...|.|||||..||.::|.|..|.|
 Worm     7 NGPPDYVEIEDRAITTEPGAS---IQAAPGAIWMEALPAIEGIPAGLEYLAYLDTVMVHQVKEVL 68

  Fly    74 ELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILDNFQNEVLHLYRPFKC- 137
            |:|||:|:||::.::|..||..|:|:|||:...|...|..|.|.|.|:|||...||.:.|..:|
 Worm    69 EILTGWESKNKYAIRNKNGQQCYYAFEESNAWERQCCGSQRGFTMHIVDNFNKNVLIVKRELRCC 133

  Fly   138 -DILC-CFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVC--PCKCFS 198
             |..| |.....|...:.:....::|:|.|........:||.:..|:.:..::|..|  .| |..
 Worm   134 ADSFCGCLLGLQNICTIESLSTGLLGTVLQGYGCTNSFYNILDKDGNLIFLVDGQGCCTSC-CCE 197

  Fly   199 DTNFKVLSANNE-EIGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFAALFLIDAVYYE 262
            |.:|.:.:.::. .||.|:|:|.||.||.|||||.|:||||::|||::||::..|.||||.|.:|
 Worm   198 DKDFTIKTPDSSVPIGSITKKWGGLLREAFTDADTFAVTFPIDLDVKLKAILLGATFLIDFVEFE 262

  Fly   263  262
             Worm   263  262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	88/227 (39%)
scrm-2	NP_493321.1	LOR	40..263	CDD:295149	87/224 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I1864
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I2390
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28609
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	1	1.000	-	-		mtm4812
orthoMCL	1	0.900	-	-		OOG6_100156
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.740