Protein Alignment scramb2 and scrm-2

DIOPT Version :10

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_493321.1
• Gene: scrm-2 / 191509
• WormBaseID: WBGene00014200
• Length: 265
• Species: Caenorhabditis elegans
• Alignment Length: 260
• Identity: 97/260 - (37%)
• Similarity: 143/260 - (55%)
• Gaps: 14/260 - (5%)

  Fly    13 NAPQD----ENGAVVLQPQAANVGNNANGPENWMSIPVGMPNCPQGLEYLTALDQLLVSQKIEKL 73
            |.|.|    |:.|:..:|.|:   ..|.....||.....:...|.|||||..||.::|.|..|.|
 Worm     7 NGPPDYVEIEDRAITTEPGAS---IQAAPGAIWMEALPAIEGIPAGLEYLAYLDTVMVHQVKEVL 68

  Fly    74 ELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILDNFQNEVLHLYRPFKC- 137
            |:|||:|:||::.::|..||..|:|:|||:...|...|..|.|.|.|:|||...||.:.|..:|
 Worm    69 EILTGWESKNKYAIRNKNGQQCYYAFEESNAWERQCCGSQRGFTMHIVDNFNKNVLIVKRELRCC 133

  Fly   138 -DILC-CFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVC--PCKCFS 198
             |..| |.....|...:.:....::|:|.|........:||.:..|:.:..::|..|  .| |..
 Worm   134 ADSFCGCLLGLQNICTIESLSTGLLGTVLQGYGCTNSFYNILDKDGNLIFLVDGQGCCTSC-CCE 197

  Fly   199 DTNFKVLSANNE-EIGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFAALFLIDAVYYE 262
            |.:|.:.:.::. .||.|:|:|.||.||.|||||.|:||||::|||::||::..|.||||.|.:|
 Worm   198 DKDFTIKTPDSSVPIGSITKKWGGLLREAFTDADTFAVTFPIDLDVKLKAILLGATFLIDFVEFE 262

  Fly   263  262
             Worm   263  262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	88/227 (39%)
scrm-2	NP_493321.1	LOR	40..263	CDD:470445	87/224 (39%)