DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scramb2 and scrm-4

DIOPT Version :9

Sequence 1:	NP_647761.1	Gene:	scramb2 / 38362	FlyBaseID:	FBgn0035390	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_492975.3	Gene:	scrm-4 / 184340	WormBaseID:	WBGene00008681	Length:	260	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	67/229 - (29%)
Similarity:	115/229 - (50%)	Gaps:	15/229 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 MSIPV--GMPNCPQG-----LEYLTALDQLLVSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAY 99
            |.:|:  ..|..|:.     |:.||:|.::.|.:.::.:|:|..:.|..|::::|..|:..|...
Worm     1 MELPIISQQPLIPEQPPTTVLQLLTSLSKVEVHEIMQPVEILADWGTAKRYQIRNENGEQCYDVL 65

  Fly   100 EESDCCTRNMLGRSRPFEMKILDNFQNEVLHLYRPFKCDILCCF------PSCMNAVEVSAPPGQ 158
            ||||...|...|..|.|.|.|.:..:.|||.:.|.|:|...||:      ..|.:...|.:|...
Worm    66 EESDGSERRFCGSQRGFVMHINNALKAEVLTVKREFRCCGGCCYGCCACVGCCQHDCVVESPTLG 130

  Fly   159 VIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVCPCKCFSDTNFKVLSANN-EEIGKISKQWSGL 222
            .:|::.|...|:...|::.:..|..:.:||.|......|.|..|.:.:.:: .|||||.::.:.|
Worm   131 TLGTIRQRFGFLTTSFDVMDGKGARIFRIEIPFWKLMGFQDKEFSIKNIDDGTEIGKIIRKTARL 195

  Fly   223 GRELFTDADYFSVTFPLNLDVRMKALIFAALFLI 256
            ..|......| ::.||.:|||::||::..|.|||
Worm   196 AGEPIVFKKY-TINFPTDLDVKLKAVLMGATFLI 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	67/229 (29%)
scrm-4	NP_492975.3	LOR	12..234	CDD:295149	64/218 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I1864
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I2390
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28609
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.840