Protein Alignment scramb2 and scrm-3

DIOPT Version :9

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_503934.2
• Gene: scrm-3 / 182212
• WormBaseID: WBGene00015437
• Length: 251
• Species: Caenorhabditis elegans
• Alignment Length: 276
• Identity: 89/276 - (32%)
• Similarity: 135/276 - (48%)
• Gaps: 48/276 - (17%)

  Fly     6 EYKVLPQNAPQ---DENGAVVLQPQAANVGNNANGPENWMSIPV--------GMP---NCPQGLE 56
            |..::|...|.   .::.|:..||.|              |||:        .:|   ..|.|||
 Worm     2 EQPLMPPAPPSYVASQSQAITTQPGA--------------SIPMPPGTIVIEALPPVEGIPGGLE 52

  Fly    57 YLTALDQLLVSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKIL 121
            ||..||.::|.|.:|.:|:.||:||||::.:|.       ..|::..||     |..|.|.|.|:
 Worm    53 YLAYLDTIMVHQFLEPIEIRTGWETKNKYAIKK-------ICYQKRQCC-----GAERAFVMHIV 105

  Fly   122 DNFQNEVLHLYRPFKCDILCCFPSCMNAVEVSAPPGQVIGSV--EQVCTFMRPKFNIKNTCGDTV 184
            |||..|||.:.|...|...||:....|...:.:|...::|:|  ...||  ....|:.:...:.:
 Worm   106 DNFNKEVLTVKRERHCCGCCCWLGSTNKSTIESPSMGLLGTVLLGHGCT--NSHCNVLDKDEELL 168

  Fly   185 LQIEGPVCPCK--CFSDTNFKVLSANN-EEIGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMK 246
            ..::|..| |.  |..|..|.:.:.:. :.||.|:|:|.|:.||.:||||.|:||||.:|||:.|
 Worm   169 FLVDGQGC-CTYCCCDDKAFTIKTPDTYKRIGAITKKWGGIIREAYTDADTFAVTFPADLDVKAK 232

  Fly   247 ALIFAALFLIDAVYYE 262
            ||:.|..|:||...:|
 Worm   233 ALLLATTFVIDFAEFE 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	82/237 (35%)
scrm-3	NP_503934.2	LOR	41..249	CDD:295149	79/223 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I1864
eggNOG	1	0.900	-	-		E1_KOG0621
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I2390
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28609
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	1	1.000	-	-		mtm4812
orthoMCL	1	0.900	-	-		OOG6_100156
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.740