Protein Alignment scramb2 and scrm-5

DIOPT Version :10

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_500500.1
• Gene: scrm-5 / 177180
• WormBaseID: WBGene00019531
• Length: 303
• Species: Caenorhabditis elegans
• Alignment Length: 268
• Identity: 73/268 - (27%)
• Similarity: 126/268 - (47%)
• Gaps: 31/268 - (11%)

  Fly    15 PQDENGAVVLQPQAANVGNNANG----PENWMSIPVGMPNCPQGL-------------EYLTAL- 61
            |:.::.....:.:||..|....|    ||. .|.|:.:||....:             ..|:|:
 Worm    27 PEQDSKKGEPRAKAAGFGGGGGGGKRLPEA-RSTPMVIPNQVAAMPVQMTGFVQLVANNILSAIA 90

  Fly    62 --DQLLVSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILDNF 124
              :.::|.|.|:.||:.|||||.||:.|.:...:.:.:..|.|:...|...|..|.|.|:|:|..
 Worm    91 HTNSVMVVQCIKPLEIFTGFETPNRYVVHDMYCRPLLYCMERSNIFARQYEGNDRNFGMQIMDTH 155

  Fly   125 QNEVLHLYRPFKCDILCCFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEG 189
            ..:|:..:|...|   |.....::...:.    |.||.:::.|  ..|.|.:..:..:..|.|:.
 Worm   156 GAQVMTCFRGRPC---CSTDDFLSTQFLD----QQIGMMKKEC--CNPNFELVGSGCNQPLLIQS 211

  Fly   190 PVCPCKCFSDTNFKVLSANNEEIGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFAALF 254
            |.| ..|.....|.|::.|...:|:|.:.:.|..:|:|||||.:.|.||:::...:|.|:..::|
 Worm   212 PGC-AGCGGTQKFPVMTFNGVLVGEIVRLYPGFMQEMFTDADTYIVHFPMDMPPILKLLLVTSVF 275

  Fly   255 LIDAVYYE 262
            |||..|:|
 Worm   276 LIDFTYFE 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	66/237 (28%)
scrm-5	NP_500500.1	Scramblase	74..284	CDD:252175	62/220 (28%)