Protein Alignment scramb2 and scrm-1

DIOPT Version :9

• Sequence 1: NP_647761.1
• Gene: scramb2 / 38362
• FlyBaseID: FBgn0035390
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_492976.2
• Gene: scrm-1 / 173053
• WormBaseID: WBGene00011935
• Length: 295
• Species: Caenorhabditis elegans
• Alignment Length: 272
• Identity: 105/272 - (38%)
• Similarity: 151/272 - (55%)
• Gaps: 20/272 - (7%)

  Fly     1 MMQMSEYKVLPQNAPQDENGAVVLQPQAANVGNNANGPENWMSIPVGMPNCPQGLEYLTALDQLL 65
            :.|...::...|.|...:.| |.:||...:|         ||.:|..:...|.||||||.||.::
 Worm    20 VQQFEMHQQQHQQAITTQPG-VFVQPAPGSV---------WMPMPPAIQGVPTGLEYLTYLDTIM 74

  Fly    66 VSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILDNFQNEVLH 130
            |.|..|.:|::|.:||||::.:||:.|:..|:|:|||.||.|...|..|.|.|.|:|||:.|||.
 Worm    75 VHQIKELIEIVTDWETKNKYVLKNANGEQCYYAFEESGCCERQCCGPQRGFVMHIVDNFKREVLT 139

  Fly   131 LYRPFK------CDILCCFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEG 189
            :.|.||      |..|.|...|.....:..|...|:|.:.|.|..|...::|.:..|:.:.||:|
 Worm   140 IKREFKCCGGGCCGCLACIGCCQQECIIETPSMGVLGIIRQRCGCMSSNYDIMDGDGNVIFQIDG 204

  Fly   190 PVC--PCKCFSDTNFKVLSANN-EEIGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFA 251
            |.|  .|.| .|..|.:.:||| ..:|.|:|:|.|..||.|||||.|:|.||.:|||::|.::..
 Worm   205 PCCCMLCGC-QDKEFPIKTANNGTVVGAITKKWGGCFREAFTDADTFAVNFPGDLDVKLKGVLIG 268

  Fly   252 ALFLIDAVYYEQ 263
            |.||||.:.:||
 Worm   269 ATFLIDFMEFEQ 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	94/229 (41%)
scrm-1	NP_492976.2	Scramblase	51..280	CDD:252175	94/229 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I1864
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I2390
Isobase	1	0.950	-	0	Normalized mean entropy	S1940
OMA	1	1.010	-	-		QHG28609
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	1	1.000	-	-		mtm4812
orthoMCL	1	0.900	-	-		OOG6_100156
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.830