DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scramb2 and plscr2

DIOPT Version :9

Sequence 1:	NP_647761.1	Gene:	scramb2 / 38362	FlyBaseID:	FBgn0035390	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_012818771.1	Gene:	plscr2 / 100489273	XenbaseID:	XB-GENE-5819744	Length:	283	Species:	Xenopus tropicalis

Alignment Length:	262	Identity:	126/262 - (48%)
Similarity:	170/262 - (64%)	Gaps:	11/262 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QMSEYKVLPQNAPQDENG-AVVLQPQAANVGNNANGPENWMSIPVGMPNCPQGLEYLTALDQLLV 66
            |.:.|...|....|.:.| |:..||......        ||.||...||||.|||||:.:||:||
Frog    28 QQNPYGYPPPGPYQFQPGQAMPTQPGVPGAA--------WMPIPAANPNCPPGLEYLSQIDQILV 84

  Fly    67 SQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILDNFQNEVLHL 131
            .|::|.||:||||||.|::::||||||.||||.||:||||||..|.||||.|.|:||...||:.|
Frog    85 HQQVELLEVLTGFETNNKYEIKNSLGQRVYFAAEENDCCTRNYCGPSRPFAMTIVDNTGREVMKL 149

  Fly   132 YRPFKCDILCCFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQIEGPVCPCKC 196
            :||.:|. .||||.|:..:||.||||.|:|.|.|......|||.|::.....||:|.||..||:|
Frog   150 HRPLRCS-ACCFPCCLQKLEVQAPPGTVVGYVVQNWHPCLPKFTIQDEREQGVLKISGPCIPCRC 213

  Fly   197 FSDTNFKVLSANNEE-IGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFAALFLIDAVY 260
            .:|.||:|:|.:... :|:|||||:|..:|:|||.|.|.:.||::||::.||::..|.||||.::
Frog   214 CTDVNFEVMSVDESSVVGRISKQWAGSVKEIFTDTDNFGIQFPMDLDIKTKAVLLGACFLIDFMF 278

  Fly   261 YE 262
            :|
Frog   279 FE 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	117/222 (53%)
plscr2	XP_012818771.1	Scramblase	60..280	CDD:252175	116/220 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	1	1.000	-	-		mtm9553
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010