DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scramb2 and plscr1

DIOPT Version :9

Sequence 1:	NP_647761.1	Gene:	scramb2 / 38362	FlyBaseID:	FBgn0035390	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_031757431.1	Gene:	plscr1 / 100216165	XenbaseID:	XB-GENE-967763	Length:	341	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	128/272 - (47%)
Similarity:	173/272 - (63%)	Gaps:	16/272 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QMSEYKVLPQNAPQDENGAVVLQPQAANVG---------NNANGP-ENWMSIPVGMPNCPQGLEY 57
            |.:..:|.|...|....|    ||..||.|         |....| ..||..|..:||||.||||
Frog    70 QTAGAQVPPGYPPGPYQG----QPGQANFGAYGGPHAVPNQPGAPAAAWMPAPAPIPNCPPGLEY 130

  Fly    58 LTALDQLLVSQKIEKLELLTGFETKNRFKVKNSLGQNVYFAYEESDCCTRNMLGRSRPFEMKILD 122
            ||.:||:||.|::|.||:||||||.|::::||||||.||||.||:||||||..|.||||.|.|:|
Frog   131 LTQIDQILVHQQVELLEVLTGFETNNKYEIKNSLGQRVYFAAEENDCCTRNCCGPSRPFSMTIVD 195

  Fly   123 NFQNEVLHLYRPFKCDILCCFPSCMNAVEVSAPPGQVIGSVEQVCTFMRPKFNIKNTCGDTVLQI 187
            |...||:.|:||.:|. .||||.|:..:||.||||..:|.|.|......|||.|::.....:|:|
Frog   196 NAGQEVMKLHRPCRCS-ACCFPCCLQKLEVQAPPGTTVGYVIQNWHPCLPKFTIQDEREQGILKI 259

  Fly   188 EGPVCPCKCFSDTNFKVLSANNEE-IGKISKQWSGLGRELFTDADYFSVTFPLNLDVRMKALIFA 251
            :||..||:|.:|..|::.|.:... :|:|:|||:|..:|.|||||.|.:.||::|||::||::..
Frog   260 KGPCIPCRCCADVKFEIKSMDESAVVGRITKQWTGFVKEAFTDADNFGIQFPMDLDVKIKAVLLG 324

  Fly   252 ALFLIDAVYYEQ 263
            |.||||.:::||
Frog   325 ACFLIDFMFFEQ 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scramb2	NP_647761.1	Scramblase	42..263	CDD:252175	113/221 (51%)
plscr1	XP_031757431.1	Scramblase	123..336	CDD:252175	110/213 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1015148at2759
OrthoFinder	1	1.000	-	-		FOG0000205
OrthoInspector	1	1.000	-	-		mtm9553
Panther	1	1.100	-	-	O	PTHR23248
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X164
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.110