Protein Alignment CG2162 and R3hcc1

DIOPT Version :9

• Sequence 1: NP_001163332.2
• Gene: CG2162 / 38360
• FlyBaseID: FBgn0035388
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_001288580.1
• Gene: R3hcc1 / 71843
• MGIID: 1919093
• Length: 502
• Species: Mus musculus
• Alignment Length: 671
• Identity: 162/671 - (24%)
• Similarity: 257/671 - (38%)
• Gaps: 242/671 - (36%)

  Fly     2 DQEFVHNVGCDIELF-VKKRLNRGVLLFPPVGNYRRYLIHQTCEKYRQQYDLF-TFSVGQGPQRR 64
            :.:|||.|..:::.| ::|:|:: |||||||.:..|||||:|.|    .:||. :||||:|.:||
Mouse    29 ENDFVHRVQEELDRFLLQKQLSK-VLLFPPVSSRLRYLIHRTAE----NFDLLSSFSVGEGWKRR 88

  Fly    65 TVLCFRNQLLDPSGFENRKQQQQREKDREREAARSWRSNNNSHYHTNGRSSSASRRSATELCKMG 129
            ||:|                                        |.:.|..|:...|..  |
Mouse    89 TVIC----------------------------------------HLDIRVPSSDGPSGP--C--- 108

  Fly   130 VKKHISETPLSKSNSVDLYRPPALRNNSNNNNSSSEEAAAVNEAITTPLAAGTATTASTSPTSKE 194
                               ||||                                   :.|:...
Mouse   109 -------------------RPPA-----------------------------------SHPSKYR 119

  Fly   195 SPNREADASAAAA-----AAATRRERRPDRAVYVPRARRSQTTPPTTTTTTTAAA---------A 245
            .|...:...|||.     |....|.|:||:.:||||..|.|..|       .||:         |
Mouse   120 GPRYTSHQGAAAGPRGAPAGRWHRGRKPDQPLYVPRVLRRQGGP-------VAASIPGIKGEDPA 177

  Fly   246 TAVATTSPPAAAA-----------VVAATITTAPD----SPP---VADTQPSKADDVNGQPPSKS 292
            .||:...|..|.|           :|...:..:||    :.|   :.||:||
Mouse   178 GAVSEEEPREAGAGDAEADQGIAMLVTQELLKSPDPGHANEPQMGLGDTEPS------------- 229

  Fly   293 KKSKSHRERRERAKKTTTATTADNATVLVISASENDTQSNEEHRPAKPADCDKEIMSGAQRTKPG 357
                   |..|:.:...||....:...|.:.      :.|..|......|.::|.:.|.:..|.
Mouse   230 -------ENPEKEQGAETAVQQGSGAQLAME------EENRSHGMRSLVDQEEEEIEGEEEEKV- 280

  Fly   358 NGNKSASNGKSQASPPLRIEDVVAARSTNGEEPAKCDNDVRELQRASKEINRSNRRIMKQTFNSD 422
             ..|....||.:.    |:::  ....|:.:| .|.|::
Mouse   281 -DEKEEDTGKQKE----RVDE--EEEKTDAQE-GKVDSE-------------------------- 311

  Fly   423 VLEIPEKIETSATKAIPTSPQASATAKPPVDSTTEDDDEEDEDDWEKMFDESGDCLDPKLLQELT 487
                .|:::....|               ||:..||:||.|.|..:  |.|        ||||:|
Mouse   312 ----GERMDEGEDK---------------VDAEEEDEDEADADHGD--FSE--------LLQEIT 347

  Fly   488 ESVGKCKIELPKMDYTVFHIKQQLLNEEEFPHVLEVSNFPVEFKTPDLLMLFAQYRGSGFDIKWV 552
            .::.:.:|::.|:........::|..|.:..|::|:.:|....||.|||..|::::..||.|:||
Mouse   348 ANLTEKEIKIEKIHLDTSAFTEELPGERDLTHLVEIYDFKPTLKTEDLLATFSEFQEKGFRIQWV 412

  Fly   553 DDTHALAVFSSSRIAAEVLTMGHPFVKLKPLAEATLESRLKAKKAGAVSMQPYRQRPETCTALAR 617
            |||||:.:|.....|.|.|......:|::||.:.|.:|:|||.:.... ::..::||:|.:|:||
Mouse   413 DDTHAIGIFPCPASALEALAKDFSVLKIRPLTQGTKQSKLKALQRPKF-LRLSKERPQTDSAVAR 476

  Fly   618 RLVSGALGV------KLPTAP 632
            |||:.|||:      :|||.|
Mouse   477 RLVARALGLQHNRKKELPTPP 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2162	NP_001163332.2	R3H	6..70	CDD:294210	32/65 (49%)
		RRM_SF	519..583	CDD:302621	24/63 (38%)
R3hcc1	NP_001288580.1	R3H_unknown_1	33..93	CDD:100067	32/104 (31%)
		RRM_SF	379..443	CDD:302621	24/63 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836917
Domainoid	1	1.000	57	1.000	Domainoid score	I10936
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002567
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21678
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3424
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.970