DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2162 and r3hcc1l

DIOPT Version :9

Sequence 1:	NP_001163332.2	Gene:	CG2162 / 38360	FlyBaseID:	FBgn0035388	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_690294.1	Gene:	r3hcc1l / 561802	ZFINID:	ZDB-GENE-030131-4156	Length:	338	Species:	Danio rerio

Alignment Length:	470	Identity:	130/470 - (27%)
Similarity:	201/470 - (42%)	Gaps:	147/470 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 ADASAAAAAAATRRERRPDRAVYVPRARRSQTTPPTTTTTTTAAAATAVATTSPPAAAAVVAATI 264
            |.....:..|...|.:||...||||:.|:::.|
Zfish     6 AQPEQGSKTAVPARTKRPTMEVYVPKKRQAEKT-------------------------------- 38

  Fly   265 TTAPDSPPVADTQPSKADDVNGQPPSKSKKSKSHRERRERAKKTTTATTADNATVLVISASENDT 329
                      |...|..|          ||||......::|:|    ...|.|.|       ::|
Zfish    39 ----------DKPQSDGD----------KKSKPRPRYTDKARK----NKKDKAKV-------SET 72

  Fly   330 QSNEEHRPAKPADCDKEIMSGAQRTKPGNGNKSASNGKSQASPPLRIEDVVAARSTNGEEPAKCD 394
            |:.|    .||.       :|.|   .|.|:....|                      .||.|.:
Zfish    73 QNGE----IKPD-------AGEQ---GGGGDTENQN----------------------TEPEKDE 101

  Fly   395 NDVRELQRASKEINRSNRRIMKQTFNSDVLEIPEKIETSATKAIPTSPQASATAKPPVDSTTEDD 459
            ....::...|:.::                                ||:.|:       |..|.|
Zfish   102 ESTGDMNTTSRTVH--------------------------------SPEDSS-------SVLEHD 127

  Fly   460 DEE---DEDDWEKMFDESGDCLDPKLLQELTESVGKCKIELPKMDYTVFHIKQQ-----LLNEEE 516
            |||   :|::|:.:|::.||||||.|::|::...|:.|.......:..::...|     .|.::|
Zfish   128 DEEMKDEEENWDSLFNDDGDCLDPHLMEEMSLKEGRKKQSAQDSGFDYYNWSPQDDEEVELRDDE 192

  Fly   517 FPHVLEVSNFPVEFKTPDLLMLFAQYRGSGFDIKWVDDTHALAVFSSSRIAAEVLTMGHPFVKLK 581
            ..|::|:.:||.||||.||:..|:.::..||||.|:||||||.:|||...|.:.|.|.:|.:|::
Zfish   193 LSHIIEIYDFPTEFKTEDLVRSFSSFQQKGFDITWIDDTHALGLFSSPIAARDALRMKNPMMKVR 257

  Fly   582 PLAEATLESRLKAKKAGAVSMQPYRQRPETCTALARRLVSGALGVKLPTAPQERENERRVLREAK 646
            ||:.::..::.||:..... :.|.::||:|..|||||||.||||||.....:|||.||..|::|:
Zfish   258 PLSSSSNATKAKARSCSDY-LLPAKERPQTSAALARRLVIGALGVKSNQTREEREAERNKLQQAR 321

  Fly   647 ERKLLAAKQRDEVWE 661
            |:|.||||||::.||
Zfish   322 EQKRLAAKQREDAWE 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2162	NP_001163332.2	R3H	6..70	CDD:294210
CG2162	NP_001163332.2	RRM_SF	519..583	CDD:302621	30/63 (48%)
r3hcc1l	XP_690294.1	RRM_PARN	195..259	CDD:240874	30/63 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580441
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D363445at33208
OrthoFinder	1	1.000	-	-		FOG0002567
OrthoInspector	1	1.000	-	-		oto38934
orthoMCL	1	0.900	-	-		OOG6_106213
Panther	1	1.100	-	-	O	PTHR21678
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3424
SonicParanoid	1	1.000	-	-		X4368
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.880