DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32487 and Hdhd2

DIOPT Version :9

Sequence 1:	NP_728791.1	Gene:	CG32487 / 38358	FlyBaseID:	FBgn0052487	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001014173.2	Gene:	Hdhd2 / 361351	RGDID:	1308579	Length:	384	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	55/244 - (22%)
Similarity:	96/244 - (39%)	Gaps:	42/244 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 LRAMGKKAFICTNNSVTSVEGICKYAQEMGFLVAKNEILSSVQTLAKFMKEKKFKKKCYVVGGQG 123
            |||........||.:..|...:.:..:::.|.:::.||.:|:......:::::
  Rat   160 LRAASVMVRFVTNTTKESKRDLLERLRKLEFDISEEEIFTSLTAARNLIEQRQ------------ 212

  Fly   124 IVDELKLVGIESLPLDHSSLQGFSMPDHIHSIYLDPNVGAVVVG-SDKDFNTIKLTKACCYLRDS 187
             |..:.||...:|| |.:.:|       .|    |||  |||:| :.:.|:...|.:|...|.|.
  Rat   213 -VRPMLLVDDRALP-DFTGVQ-------TH----DPN--AVVIGLAPEHFHYQLLNEAFRLLLDG 262

  Fly   188 EVMFVA-----TSRDAALPAAPGRMVPSAGVMVAAIQAASQRMPFTCGKPNPYMCIDLMQKGVIQ 247
            ..:...     ..|...|...|       |..|.|::.|:.......|||.....::.::.....
  Rat   263 APLIAIHKARYYKRKDGLALGP-------GPFVTALEYATDTKAVVVGKPEKTFFLEALRDTDCA 320

  Fly   248 PDRTLIIGDTMCTDILLGYKCGFQTLLVGTGVNSYQDAIEAQGSKAPLL 296
            |:..::|||....|:......|...:||.||  .|:.|.|.:.:..|.|
  Rat   321 PEEAVMIGDDCRDDVDGAQNIGMLGILVKTG--KYKAADEEKINPPPYL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32487	NP_728791.1	PGP_euk	30..311	CDD:273635	55/244 (23%)
		Hydrolase_6	34..134	CDD:290083	13/74 (18%)
		Hydrolase_like	229..>281	CDD:289983	13/51 (25%)
Hdhd2	NP_001014173.2	Yos1	5..>64	CDD:285740
		HAD-SF-IIA-hyp3	122..382	CDD:162372	55/244 (23%)
		HAD_like	<159..>211	CDD:304363	10/50 (20%)
		Hydrolase_like	301..375	CDD:289983	18/69 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810