DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32487 and pho2

DIOPT Version :9

Sequence 1:	NP_728791.1	Gene:	CG32487 / 38358	FlyBaseID:	FBgn0052487	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_596255.1	Gene:	pho2 / 2539960	PomBaseID:	SPBC15D4.15	Length:	298	Species:	Schizosaccharomyces pombe

Alignment Length:	297	Identity:	90/297 - (30%)
Similarity:	140/297 - (47%)	Gaps:	24/297 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 QQWLKTIDTIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGF 89
            ::::...|..:||.:|||||..|.:....:|...||::||:....:|||..|.|.......|.|.
pombe    12 KEFIDKFDVFLFDCDGVLWSGSKPIPGVTDTMKLLRSLGKQIIFVSNNSTKSRETYMNKINEHGI 76

  Fly    90 LVAKNEILSSVQTLAKFMKEKKFK----KKCYVVGGQGIVDELKLVGIESLPLDHSSLQGFSMPD 150
            .....||..|..:.|.::| |..|    ||.:|:|..||.|||..||:..:.....||:.....:
pombe    77 AAKLEEIYPSAYSSATYVK-KVLKLPADKKVFVLGEAGIEDELDRVGVAHIGGTDPSLRRALASE 140

  Fly   151 HIHSIYLDPNVGAVVVGSDKDFNTIKLTKACCYLRDSEVMFVATSRDAALPAAPGRMVPSAGVMV 215
            .:..|..||:||||:.|.|.....:|...|..||:|....|:.|::|:..| ..|:.:|.:|.:.
pombe   141 DVEKIGPDPSVGAVLCGMDMHVTYLKYCMAFQYLQDPNCAFLLTNQDSTFP-TNGKFLPGSGAIS 204

  Fly   216 AAIQAASQRMPFTCGKPNPYMCIDLMQKGVI-----QPDRTLIIGDTMCTDILLGYKCGF-QTLL 274
            ..:..::.|.|...|||     .|.|.:.:|     ...:...:||.:.|||........ .:||
pombe   205 YPLIFSTGRQPKILGKP-----YDEMMEAIIANVNFDRKKACFVGDRLNTDIQFAKNSNLGGSLL 264

  Fly   275 VGTGVNSYQDAIEAQGSKAPLLYQQVPDLYMPKLSNL 311
            |.|||:..::.:|   ..||:    |||.|:..|:.|
pombe   265 VLTGVSKEEEILE---KDAPV----VPDYYVESLAKL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32487	NP_728791.1	PGP_euk	30..311	CDD:273635	89/290 (31%)
		Hydrolase_6	34..134	CDD:290083	38/103 (37%)
		Hydrolase_like	229..>281	CDD:289983	17/57 (30%)
pho2	NP_596255.1	NagD	11..298	CDD:223720	90/297 (30%)
		Hydrolase_6	21..123	CDD:290083	37/102 (36%)
		Hydrolase_like	217..294	CDD:289983	25/88 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	78	1.000	Domainoid score	I2380
eggNOG	1	0.900	-	-		E1_COG0647
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	169	1.000	Inparanoid score	I1198
OMA	1	1.010	-	-		QHG60740
OrthoFinder	1	1.000	-	-		FOG0000783
OrthoInspector	1	1.000	-	-		otm47201
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X675
TreeFam	1	0.960	-	-
	10	9.830