Protein Alignment FMRFaR and Proc-R

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_572183.1
• Gene: Proc-R / 31408
• FlyBaseID: FBgn0029723
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 536
• Identity: 107/536 - (19%)
• Similarity: 176/536 - (32%)
• Gaps: 208/536 - (38%)

  Fly   118 VLINIVGVLGILGNIISMIILSRPQMRSSINYLLTGLARCDTVLIITSILLFGIPSI--YPYTGH 180
            :|:..|.|:|:|||.:|:.:|:|.:||.:.|..||.||..|...:...::|    |:  |.|..:
  Fly    45 ILVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIAYLTCQLIL----SLQHYDYPKY 105

  Fly   181 FFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVCV 245
            .|..|..:|.:........|.|    |||:....|:||::|:.:|||.:..||...||.......
  Fly   106 HFKLYWQLYGYFVWLCDSFGYI----SIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVA 166

  Fly   246 CFSL---------------------AY-------------------------------------- 251
            .|.|                     ||
  Fly   167 IFCLLSTLSTAFEHTITIGTRQIDDAYQPCNQTVANISPMPPPPVAVTPPLATPPLPTPATIWQS 231

  Fly   252 -----------------------------NMP---RFWE--------VLTVTYPEPGKDV----- 271
                                         |:|   |.|:        .|..|..|..:.|
  Fly   232 PDSAMESTTSGSSNQLVDWGSGSGDGEPENIPRHRRHWQSSGFVTLPTLRKTLEEQDQKVADAAQ 296

  Fly   272 -------ILHCVRPSRLRRSETY------------------INIYIH----------WCY----- 296
                   :|...|  |.|.:|.:                  :..|.|          :.|
  Fly   297 RSGVTESLLQLWR--RKRSAENHNINNTDAFAFNVTEYCQNVTYYNHGLSELGYDELYSYLWNLF 359

  Fly   297 -LIVNYIIPFLTLAILNCLIYRQVKRANRERQRLSRS-------EKREIGL---------ATMLL 344
             |:|..:.|.|.||..|.::...|.|:...|..|:.:       .|...||         .|:.|
  Fly   360 TLLVFVVFPLLLLATFNSILILLVHRSKNLRGDLTNASSIRRTKRKSNSGLKGSVSQENRVTITL 424

  Fly   345 CVVIVFFMLNFLP--LVLNISEAFYSTIDHKIT--KISNLLITINSSVNFLIYIIFGEKFKRIFL 405
            ..|::.|::..||  :.|.:::.....|..::.  .:.|||.:::::.||.:|.:..:|:::...
  Fly   425 IAVVLMFIVCQLPWAIYLIVNQYMEIQIGTQVVAGNVCNLLASLHAASNFFLYCVLSDKYRKTVR 489

  Fly   406 LIF----FKRRLSRDQPDLIHYESSISNNGDGTLNHRSSGRFSRHGTQRSTTTTYLVATGGPGGG 466
            .:.    ::||.:|:...|                      :..|     ||||.....|...|.
  Fly   490 ELITGYRYRRRHARNNTSL----------------------YVPH-----TTTTLTQINGDHYGS 527

  Fly   467 GCGGGGGNNSLNNVRL 482
            ..||.|...:.|..||
  Fly   528 NYGGAGSRRNRNTGRL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	90/452 (20%)
		TM helix 1	115..141	CDD:410630	9/22 (41%)
		TM helix 2	147..172	CDD:410630	7/24 (29%)
		TM helix 3	193..223	CDD:410630	9/29 (31%)
		TM helix 4	235..255	CDD:410630	8/110 (7%)
		TM helix 5	289..314	CDD:410630	10/40 (25%)
		TM helix 6	334..362	CDD:410630	10/38 (26%)
		TM helix 7	372..397	CDD:410630	6/26 (23%)
Proc-R	NP_572183.1	7tmA_FMRFamide_R-like	41..488	CDD:410630	90/452 (20%)
		TM helix 1	42..68	CDD:410630	9/22 (41%)
		TM helix 2	74..99	CDD:410630	8/28 (29%)
		TM helix 3	114..144	CDD:410630	10/33 (30%)
		TM helix 4	156..176	CDD:410630	4/19 (21%)
		TM helix 5	351..378	CDD:410630	8/26 (31%)
		TM helix 6	415..445	CDD:410630	7/29 (24%)
		TM helix 7	456..481	CDD:410630	6/24 (25%)