DRSC/TRiP Functional Genomics Resources

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Protein Alignment FMRFaR and Gpr139

DIOPT Version :9

Sequence 1:NP_001261347.1 Gene:FMRFaR / 38357 FlyBaseID:FBgn0035385 Length:549 Species:Drosophila melanogaster
Sequence 2:NP_001019412.1 Gene:Gpr139 / 293545 RGDID:1311729 Length:345 Species:Rattus norvegicus


Alignment Length:372 Identity:84/372 - (22%)
Similarity:152/372 - (40%) Gaps:88/372 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 CG------VLINIVGVLGILGNIISMIILSR---PQMRSSINYLLTGLARCDTVLIITSILLFGI 171
            ||      |..:.:..||:..||:::||||:   .:.:||.|||| .||..| :|::..|:... 
  Rat    15 CGLGFVPVVYYSFLLCLGLPANILTVIILSQLVARRQKSSYNYLL-ALAAAD-ILVLFFIVFVD- 76

  Fly   172 PSIYPYTGHFFGYYNYVYPFISPAVFPIGMI------AQTASIYMTFTVTLERYVAVCHPLKARA 230
                      |...:::.....|.: |..:|      :...||::|..:|::||:|||||||...
  Rat    77 ----------FLLEDFILTMQMPPI-PDKIIEVLEFSSIHTSIWITVPLTVDRYIAVCHPLKYHT 130

  Fly   231 LCTYGRAK----IYFIVCVCFSLAYN-MPRFWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINI 290
            :....|.:    ..:|.|...|:.|. .|..|                          :|.||:.
  Rat   131 VSYPARTRKVILSVYITCFLTSIPYYWWPNIW--------------------------TEDYIST 169

  Fly   291 YIH----WCYLIVNYIIPFLTLAILNCLIYRQVKRANRERQRLSRSEKREIGLATMLLCVVIVFF 351
            .:|    |.:....|::|.....|||.:|..:::|.:..|.|     ....|..|.:|..:...|
  Rat   170 SMHHVLVWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLR-----GYSTGKTTAILFTITSIF 229

  Fly   352 MLNFLPLVLNISEAFYST------IDHKITKISNLLITINSSVNFLIYIIFGEKFKRI---FLLI 407
            ...:.|.::.|....|..      :.|.:..::|:|..:|:::||.:|....::|:.:   .|..
  Rat   230 ATLWAPRIIMILYHLYGAPIQNPWLVHIMLDVANMLALLNTAINFFLYCFISKRFRTMAAATLKA 294

  Fly   408 FFKRRLSRDQPDLIHYESSISNNGDGTLNHRSSG-------RFSRHG 447
            .||   .:.||...:...:.|......::..:|.       ::.:||
  Rat   295 LFK---CQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKHG 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FMRFaRNP_001261347.1 7tm_4 122..394 CDD:304433 70/295 (24%)
7tm_1 130..393 CDD:278431 68/286 (24%)
Gpr139NP_001019412.1 7tmA_GPR139 19..288 CDD:320585 73/313 (23%)
TM helix 1 21..45 CDD:320585 8/23 (35%)
TM helix 2 55..77 CDD:320585 9/34 (26%)
TM helix 3 94..116 CDD:320585 4/21 (19%)
TM helix 4 139..155 CDD:320585 3/15 (20%)
TM helix 5 173..196 CDD:320585 5/22 (23%)
TM helix 6 219..241 CDD:320585 4/21 (19%)
TM helix 7 256..281 CDD:320585 7/24 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166351862
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm9117
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.840

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