Protein Alignment FMRFaR and W10C4.1

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_497177.3
• Gene: W10C4.1 / 189329
• WormBaseID: WBGene00021124
• Length: 398
• Species: Caenorhabditis elegans
• Alignment Length: 423
• Identity: 88/423 - (20%)
• Similarity: 151/423 - (35%)
• Gaps: 119/423 - (28%)

  Fly   106 LENNRIEFWVCGVLINIVGVLGILGNIISMIILSRPQMRSSINYLLTGLARCDTVLIITSILLFG 170
            |..:.:|.::..||...:.:.|::||.:::::|......|..|..||.||.||     .|.|:..
 Worm    15 LSGSNLEAFLYTVLFPPICLFGVVGNALTILVLVNNDFMSRANIFLTCLAVCD-----VSFLILI 74

  Fly   171 IPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTA--SIYMTFTVTLERYVAVCHPLKARALCT 233
            ||........|...|.:.|.::...:..|.....|:  :|::...|..||...|..||  ..|.|
 Worm    75 IPHSLANFDRFAFNYTFRYLYLPSKMHLIAFANWTSAVAIWLVVGVCFERVAGVRSPL--HRLTT 137

  Fly   234 YGRAK-----IYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHC------------------ 275
            ..|.|     :..:.|......||                 .|..||
 Worm   138 PSRGKLTTGLLTLLTCCAALTFYN-----------------HVSHHCFIKSFCNATQIMAVCLDV 185

  Fly   276 -----------VRPSRLRRSETYI------NIYIHWCYLIVNYIIPFLTLAILNCLIYRQVKRAN 323
                       :.|..||   ||:      |     ..|:|  .:|.:.|.:||.::...||:.:
 Worm   186 NLDVWPNNRTNISPPALR---TYVAATRAAN-----AALVV--FLPMILLVVLNMMLLYYVKKRS 240

  Fly   324 --------RERQRLSRS---------------------EKREIGLATMLLCVVIVFFMLNFLP-- 357
                    |...|:.:|                     ::|......:.:|.|:..|.:...|
 Worm   241 FFMYASLGRVSARMRKSGGDVALPFVGTLFRRHSDQILQQRTEHRVAVTVCAVVTSFTITQAPSA 305

  Fly   358 LVLNISEAFYSTID---HKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRLSRDQPD 419
            :||.::......:|   :.:|.|::.|:.|..|:||:::.:....|:|........:..|||:
 Worm   306 VVLTVNSLLKERLDAHWYHMTTITSFLVVIGKSLNFVVFCLSSSSFRRRLTNTLRSKYGSRDE-- 368

  Fly   420 LIHYESSISNNGDGTLNHRSSGRFSRHGTQRST 452
                :.|.|.|   |...|...|.||..:|:.:
 Worm   369 ----KRSHSIN---TTYTRCDSRDSRILSQKKS 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	74/365 (20%)
		TM helix 1	115..141	CDD:410630	6/25 (24%)
		TM helix 2	147..172	CDD:410630	9/24 (38%)
		TM helix 3	193..223	CDD:410630	6/31 (19%)
		TM helix 4	235..255	CDD:410630	5/24 (21%)
		TM helix 5	289..314	CDD:410630	7/24 (29%)
		TM helix 6	334..362	CDD:410630	7/29 (24%)
		TM helix 7	372..397	CDD:410630	7/24 (29%)
W10C4.1	NP_497177.3	7tmA_FMRFamide_R-like	23..355	CDD:410630	74/365 (20%)
		TM helix 1	24..50	CDD:410630	6/25 (24%)
		TM helix 2	56..81	CDD:410630	11/29 (38%)
		TM helix 3	99..129	CDD:410630	6/29 (21%)
		TM helix 4	141..161	CDD:410630	2/19 (11%)
		TM helix 5	206..231	CDD:410630	7/31 (23%)
		TM helix 6	281..311	CDD:410630	7/29 (24%)
		TM helix 7	323..348	CDD:410630	7/24 (29%)