Protein Alignment FMRFaR and frpr-10

DIOPT Version :9

• Sequence 1: NP_001261347.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001379889.1
• Gene: frpr-10 / 186481
• WormBaseID: WBGene00019019
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 296
• Identity: 78/296 - (26%)
• Similarity: 131/296 - (44%)
• Gaps: 60/296 - (20%)

  Fly   180 HFFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVC 244
            |||..       ::.::||:.:|||..|::....||::|::|||.|:|.|...|.........|.
 Worm    25 HFFWR-------VTVSIFPLSLIAQAGSVWTYVAVTVDRFIAVCFPIKRRVWSTRSNTITVLFVI 82

  Fly   245 VCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINIYIHWCYLIVNYIIPFLTLA 309
            ...|..:.:|.|:||......|         |.|:.||::|.||..|:.:.|:....:||:..:.
 Worm    83 TFISAIFKLPSFFEVRLDHNGE---------VEPTELRKNEFYIEFYLFYLYVTFIQLIPWTLII 138

  Fly   310 ILNCLIYRQVKRANRERQRL--------SRSEKREIGLATMLLCVVIVFFMLNFLPLVLNISEAF 366
            .||.:|..:|:.|.|.::.:        ::.|..|..:..|...:.::|.:.| :|..:|.....
 Worm   139 FLNAIIIHKVRLAYRAQEAMVHNSGKLNTKREDAERKVTVMATVMTMIFIICN-IPPGINYLVDR 202

  Fly   367 YS--TIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLI-----FFKRRLSRDQPDLIHYE 424
            ||  |:..:...:||:|:.:||:.|.:||.:|..:|:|..|.:     ||..|
 Worm   203 YSNPTVYRQRIPLSNVLVCVNSASNMMIYCVFNSRFRRAALKLLGCPSFFSSR------------ 255

  Fly   425 SSISNNGDGTLNHRS-SGRFSRH---GTQRSTTTTY 456
                        |.| |.|.:|.   |..||...||
 Worm   256 ------------HGSVSTRLTREETTGMLRSRVATY 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_001261347.1	7tm_4	122..394	CDD:304433	60/223 (27%)
		7tm_1	130..393	CDD:278431	59/222 (27%)
frpr-10	NP_001379889.1	7tmA_FMRFamide_R-like	<20..242	CDD:410630	64/233 (27%)
		TM helix 3	32..54	CDD:410630	7/21 (33%)
		TM helix 4	77..93	CDD:410630	2/15 (13%)
		TM helix 5	119..142	CDD:410630	5/22 (23%)
		TM helix 6	177..199	CDD:410630	5/22 (23%)
		TM helix 7	210..235	CDD:410630	8/24 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BKGC
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8000
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46641
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.820