Protein Alignment FMRFaR and dmsr-1

DIOPT Version :9

• Sequence 1: NP_001261347.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_741629.1
• Gene: dmsr-1 / 186437
• WormBaseID: WBGene00010191
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 114/535 - (21%)
• Similarity: 204/535 - (38%)
• Gaps: 150/535 - (28%)

  Fly   102 YNPLLENNRIEFWVCGVLINIVGVLGILGNIISMIILSRPQMRSSINYLLTGLARCDTVLIITSI 166
            |:|:  :..:..::|        |||.:.|..::::|:|..||:.:|.:||.:|.||||::.:::
 Worm    30 YHPI--HAYLSIFLC--------VLGTIANFCNIVVLTRRTMRTPVNMILTAMASCDTVVLFSNL 84

  Fly   167 LLFGIPSIYPYTGHF-FGYYNYVYP---FISPAVFPI-----GMIAQTASIYMTFTVTLERYVAV 222
            :         ||.|: |..:.:.:|   ..|.|:|.|     .::|.::|::::..:.|.|||.
 Worm    85 I---------YTTHYSFVAFKFCHPKHWSYSWALFLIAHAHLSLVAHSSSVWLSVMLALVRYVT- 139

  Fly   223 CHPLKARALCTYGRAKI-----YFIVCVCFSL--AYNMPRFWEVL--------TVTYPEPGKDVI 272
               |::|.  ..|..::     |:.|.|..||  ..|.|.|....        |.|..:|
 Worm   140 ---LRSRG--NMGGMQVTLRHSYYAVAVTVSLVAVLNAPNFLNYKINEQPLNETCTDLDP----- 194

  Fly   273 LHCVRPSRL-------RRSETYINIYIHWCYLIVNYIIPFLTLAILNCLIYRQVK--RANRER-- 326
            :....|:.|       :.:...:....:|...:|..::|...|::...|:.|.::  |.||:|
 Worm   195 MFWNSPAYLPGIADIAKANSCLVFRLSYWISGMVFKVLPCALLSLFVWLLLRILREVRENRQRLL 259

  Fly   327 ----------------QRLS---------------RSEKREIGLATMLLCVVIVFFMLNFLP--- 357
                            ||||               |.....:...|.:|..::...::..||
 Worm   260 KNSQHRPPNQTTTRNGQRLSISVAGNEKLGRNGSLRGRGERVDRTTHMLLAIVAVMLVTELPQGI 324

  Fly   358 -LVLN--ISEAFYSTIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFK---RRLSRD 416
             .||:  .||.|...|.:.:..|.:|.....|..:|:||.....:|:..|..:|..   |.|...
 Worm   325 MAVLSGMCSEEFRIYIYNNLGDILDLFSLCGSCCSFIIYCSMSGQFRNEFHRVFVPAKVRCLRMS 389

  Fly   417 QPDLIHYESSISNNGDGTLNHRSSGRFSRHGTQRSTTTTYLVATGGPGGGGCGGGGGNNSLNNVR 481
            .|.:                .|.|..:|      :|..|:|......|.|..|.|..:....:..
 Worm   390 SPSI----------------RRPSDAYS------TTKMTFLKPNEKNGNGMNGNGTYSEDTRSAS 432

  Fly   482 LTQVSGSPGLVKIKRNRAP-------------SPGPVVYFPAREMQ--RSA--STTNSTTNNNTS 529
            :..|.     ::::||...             ||.| ..||:..:.  ||.  .:|:.|::...|
 Worm   433 VKMVG-----IQVRRNSTEITRMTGCDSITPCSPMP-TSFPSSPLPPIRSGEDESTDETSHLLNS 491

  Fly   530 IGYDWTLPDSKKLGH 544
            .|.:.|.......||
 Worm   492 SGPNSTASADGIRGH 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_001261347.1	7tm_4	122..394	CDD:304433	77/343 (22%)
		7tm_1	130..393	CDD:278431	73/334 (22%)
dmsr-1	NP_741629.1	7tmA_FMRFamide_R-like	32..374	CDD:410630	81/371 (22%)
		TM helix 1	34..58	CDD:410630	6/31 (19%)
		TM helix 2	66..88	CDD:410630	9/30 (30%)
		TM helix 3	112..134	CDD:410630	3/21 (14%)
		TM helix 4	158..174	CDD:410630	5/15 (33%)
		TM helix 5	219..242	CDD:410630	4/22 (18%)
		TM helix 6	305..327	CDD:410630	4/21 (19%)
		TM helix 7	342..367	CDD:410630	6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910