Protein Alignment FMRFaR and dmsr-4

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001368505.1
• Gene: dmsr-4 / 183924
• WormBaseID: WBGene00017038
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 336
• Identity: 76/336 - (22%)
• Similarity: 153/336 - (45%)
• Gaps: 46/336 - (13%)

  Fly   125 VLGILGNIISMIILSRPQM-RSSINYLLTGLARCDTVLIITSILLFGIPSIYPYTGHFFGYYNYV 188
            ::|:..|.|.:.:||||:| |.::|.:||.:|.|| |:.:||..::.:...:..|.|.:.|...|
 Worm    51 IVGVFSNAIHIAVLSRPRMRRCAVNSVLTAVAFCD-VITMTSYSIYLMRFRFYETDHGYSYIWLV 114

  Fly   189 YPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVCVCFSLAYNM 253
              |:...|:. .|.....::||...:...|:.|:.: :.::.|......:::.:|.|..|:.. :
 Worm   115 --FLKFHVWS-SMTLHAITLYMGGALAFIRWQALGN-IHSKWLQPRNSWQLFGVVSVVLSIVC-L 174

  Fly   254 PR--FWEVLTVTYPEPGKDVILHCVR------PSRLRRS---ETYINIYIH---WCYLIVNYIIP 304
            |.  ..::..:..||.....:...:|      |..:|.|   .||...:..   |...||...||
 Worm   175 PTLVLHKIYEIESPEIETSTVSEVLRLSGQSIPKEVRYSLNFSTYSCAFFKFNLWMLAIVLKAIP 239

  Fly   305 FLTLAILNCLIYRQVKRANRERQRL-SRSEKREIGLATM------LLCVVIVFFMLNFLPL-VLN 361
            ...|......:..::::.:.:|..| |:|.::.:...|:      :|.:::|.|::..||. .|.
 Worm   240 CALLLWFTIALVVKLRQTDEKRNYLYSKSFRKHVKKTTVPDRTTYMLIIMLVVFLVTELPQGFLA 304

  Fly   362 ISEAFYS-----TIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRLSRDQPDLI 421
            :....|:     .|...::::.:.|..||.||:||:|.:...::::.|..:            ||
 Worm   305 LLNGLYTGDVNIYIYKNLSELLDFLSLINCSVDFLLYCVMSSRYRQTFGHM------------LI 357

  Fly   422 HYESSISNNGD 432
            ..||.:.|:|:
 Worm   358 RVESWLRNHGE 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	69/306 (23%)
		TM helix 1	115..141	CDD:410630	5/15 (33%)
		TM helix 2	147..172	CDD:410630	9/24 (38%)
		TM helix 3	193..223	CDD:410630	6/29 (21%)
		TM helix 4	235..255	CDD:410630	3/19 (16%)
		TM helix 5	289..314	CDD:410630	6/27 (22%)
		TM helix 6	334..362	CDD:410630	7/34 (21%)
		TM helix 7	372..397	CDD:410630	8/24 (33%)
dmsr-4	NP_001368505.1	7tmA_FMRFamide_R-like	40..352	CDD:410630	69/306 (23%)
		TM helix 1	41..67	CDD:410630	5/15 (33%)
		TM helix 2	74..99	CDD:410630	9/25 (36%)
		TM helix 3	116..146	CDD:410630	6/30 (20%)
		TM helix 4	156..176	CDD:410630	3/20 (15%)
		TM helix 5	224..249	CDD:410630	6/24 (25%)
		TM helix 6	277..307	CDD:410630	7/29 (24%)
		TM helix 7	320..345	CDD:410630	8/24 (33%)