Protein Alignment FMRFaR and frpr-4

DIOPT Version :10

• Sequence 1: NP_647758.1
• Gene: FMRFaR / 38357
• FlyBaseID: FBgn0035385
• Length: 549
• Species: Drosophila melanogaster
• Sequence 2: NP_001309544.1
• Gene: frpr-4 / 183763
• WormBaseID: WBGene00016909
• Length: 362
• Species: Caenorhabditis elegans
• Alignment Length: 379
• Identity: 103/379 - (27%)
• Similarity: 182/379 - (48%)
• Gaps: 66/379 - (17%)

  Fly    96 RICEDVYNPLLENNRIEFWVCGVLINIVGVLGILGNIISMIILSRPQMRSSINYLLTGLARCDTV 160
            ||...||.|.:                  ::|:|||::|:...||...:|.:.:||..|:..|..
 Worm     9 RIMAFVYLPTI------------------LIGLLGNLLSLYAYSRKNRKSMVGFLLYSLSVSDIF 55

  Fly   161 LIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTFTVTLERYVAVCHP 225
            |::.::.||.|..:..:|..   ..::|..:.:..|:|:.|:|:|.|:|:...:|:||::|||.|
 Worm    56 LLVFALPLFSIMYLPIWTDE---QRSFVVAYTAKYVYPLCMMAKTCSLYIMVLITIERWIAVCRP 117

  Fly   226 LKARALCTYGRAKIYFIVCVCFSLAYNMPRFWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINI 290
            |:.:..|.|..:.......:.|::..|..||:| ..:.|.:.     |...|...|...:
 Worm   118 LEVQIWCRYTTSSYSIAAIITFAVVLNFARFFE-FEIEYIDG-----LAFFRRDLLDSEK----- 171

  Fly   291 YIHWCY---------LIVNYIIPFLTLAILNCLIYRQVKRANRERQRLSRSEKREIGLATMLLCV 346
              ||.|         :|.:|::||:.:.:.|.||..:::|..:||..::..:::|.....|||.:
 Worm   172 --HWWYFMFYFIIISIIFDYLVPFVIMFVANMLIISELRRTKKERSLMTIQQQKEQNTTVMLLVI 234

  Fly   347 VIVFFMLNFLPLVLNISEAF---YSTIDH----KITKISNLLITINSSVNFLIYIIFGEKFKRIF 404
            .|.|...:|..:.|.::|:|   :.||.:    .:.:|.|.||.|:::..|.||.:|.|||::|.
 Worm   235 TIFFGFCHFFSMALKLAESFVGKFLTIQNIYLEMLGEIFNYLIIIHTASTFFIYYMFSEKFRQII 299

  Fly   405 LLIFFKRRLSRDQPDLIHYESSISNNGDGTLNHRSS--GRFSRHGTQRSTTTTY 456
            ..|:        :||...:.|.    .|||||...|  .:.:|||:  ||...|
 Worm   300 KGIW--------KPDQYRHGSL----PDGTLNITDSKKRKINRHGS--STKIMY 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_647758.1	7tmA_FMRFamide_R-like	114..404	CDD:410630	81/305 (27%)
		TM helix 1	115..141	CDD:410630	6/25 (24%)
		TM helix 2	147..172	CDD:410630	7/24 (29%)
		TM helix 3	193..223	CDD:410630	11/29 (38%)
		TM helix 4	235..255	CDD:410630	2/19 (11%)
		TM helix 5	289..314	CDD:410630	8/33 (24%)
		TM helix 6	334..362	CDD:410630	8/27 (30%)
		TM helix 7	372..397	CDD:410630	8/28 (29%)
frpr-4	NP_001309544.1	7tmA_FMRFamide_R-like	33..299	CDD:410630	76/281 (27%)
		TM helix 2	42..67	CDD:410630	7/24 (29%)
		TM helix 3	85..115	CDD:410630	11/29 (38%)
		TM helix 4	127..147	CDD:410630	2/19 (11%)
		TM helix 5	177..202	CDD:410630	5/24 (21%)
		TM helix 6	222..252	CDD:410630	8/29 (28%)
		TM helix 7	265..292	CDD:410630	8/26 (31%)