DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FMRFaR and LOC100488533

DIOPT Version :9

Sequence 1:	NP_001261347.1	Gene:	FMRFaR / 38357	FlyBaseID:	FBgn0035385	Length:	549	Species:	Drosophila melanogaster
Sequence 2:	XP_002942420.1	Gene:	LOC100488533 / 100488533	-ID:	-	Length:	321	Species:	Xenopus tropicalis

Alignment Length:	370	Identity:	67/370 - (18%)
Similarity:	132/370 - (35%)	Gaps:	105/370 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 YEDLGLDPDPNWTRICEDVYNPLLENNRIEFWVCGVLINIVGVLGILGNIISMIILSRPQMRSSI 147
            |.|..|...|..:|     :.|||   .|.|:...::|       :.||.:.:.::...:...|.
Frog    14 YTDFTLLGFPGISR-----WRPLL---AIPFFTMYLVI-------LSGNSLLICLICIKKTLHSP 63

  Fly   148 NYLLTGLARCDTVLIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFPIGMIAQTASIYMTF 212
            .|||        :.::.:|.:....:|.|             .|:...:|.:..::.|..:...|
Frog    64 MYLL--------ISVLFAIHITSCTAILP-------------KFLLDLLFQLNQVSLTGCLLQMF 107

  Fly   213 TV--------------TLERYVAVCHPLKARALCTYG-RAKIYFIV------CVC-FSLAYNMPR 255
            .:              :|:||||:|.||....:.|.. ...:.|::      .|| |.:..:|.:
Frog   108 VIYFMAVCESNVMVLMSLDRYVAICRPLHYHNIMTKRFLVSLTFVIIIQSFALVCPFVIFPSMTQ 172

  Fly   256 FWEVLTVTYPEPGKDVILH------------CVRPSRLRRSETYINIYIHWCYLIVNYIIP---- 304
            |.:          .:.|||            |...::|.::.           ||:..::|
Frog   173 FCK----------SNTILHFACEHLALLSLGCGDTTKLEKAG-----------LIIRILVPVRDG 216

  Fly   305 FLTLAILNCLIYRQVKRANRERQRLSRSEKREIG-LATMLLCVVIVFFMLNFLPLVLNISEAFYS 368
            .|.:...:.::|..:|.|.      .:|..:.:. ..|.||..|:.:........|..:......
Frog   217 ILLMISYSTILYTAMKTAT------GKSRHKALNTCGTHLLVAVLAYVCALASSSVWKVEATVSE 275

  Fly   369 TIDHKITKISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRL 413
            .:.|..|.   |.|.|.::.|..||.:...|.::..:..:.:|::
Frog   276 DVKHLFTA---LYIVIPAASNPFIYGLRISKIRKTLVKYWRERKI 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FMRFaR	NP_001261347.1	7tm_4	122..394	CDD:304433	53/310 (17%)
FMRFaR	NP_001261347.1	7tm_1	130..393	CDD:278431	52/301 (17%)
LOC100488533	XP_002942420.1	7tm_GPCRs	30..305	CDD:391938	61/335 (18%)
		TM helix 1	32..56	CDD:341315	6/33 (18%)
		TM helix 2	65..87	CDD:341315	6/42 (14%)
		TM helix 3	103..125	CDD:341315	1/21 (5%)
		TM helix 4	148..164	CDD:341315	3/15 (20%)
		TM helix 5	201..224	CDD:341315	4/33 (12%)
		TM helix 6	240..265	CDD:341315	4/24 (17%)
		TM helix 7	276..301	CDD:341315	8/27 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1342402at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010