Protein Alignment CPT2 and YAT1

DIOPT Version :9

• Sequence 1: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_009420.1
• Gene: YAT1 / 851285
• SGDID: S000000080
• Length: 687
• Species: Saccharomyces cerevisiae
• Alignment Length: 716
• Identity: 210/716 - (29%)
• Similarity: 329/716 - (45%)
• Gaps: 156/716 - (21%)

  Fly    44 SLPRLPIPLLENSCRRFLEATKPLLSPAEQAQTQQTVEQFRQGIGME-------LHAKLKSHDA- 100
            :|.|||||.|:::..|:|...:||....:..:|::||      :..|       ||.:|..:||
Yeast     3 NLKRLPIPPLQDTLNRYLARVEPLQDERQNRRTRRTV------LSAENLDALNTLHERLLEYDAR 61

  Fly   101 ---ENKHTSYISQPWFDMYLADRAPLPLNYNPLLVMKSDA----RPE---------YQQQVVRAT 149
               .|..:|||.|.|:|.||...|.:.||.||...::.|.    .||         :..||.||.
Yeast    62 LAESNPESSYIEQFWYDAYLLYDATVVLNVNPYFQLQDDPTIKDTPETAAQGPYGAHTVQVRRAA 126

  Fly   150 NLIISSLRFWRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAPKAFATYASYAFKAFPLDMSQYN 214
            .|..|.|:|.|.::...|          ::||        |..|.            ||.|.||.
Yeast   127 RLTTSILKFIRQIRHGTL----------RTDT--------VRGKT------------PLSMDQYE 161

  Fly   215 RLFGTSRIPRIGKDE----LVQSPDAKHILVMRRGHMYAVNVLDSSG--YIESPSVILGRLRAVL 273
            ||||:||||. |..|    |.....:.|::.|.||..|..:|||:..  ...:|..:...|.:::
Yeast   162 RLFGSSRIPP-GPGEPSCHLQTDATSHHVVAMYRGQFYWFDVLDTRNEPIFATPEQLEWNLYSII 225

  Fly   274 KLDADRE-AASVPLGVLTSGQRDEWAKTRQHF-----VSNTKNADLLEREVDAALFCVCLDGEED 332
             :||:.. :.|.|.||.|:..|..|:..|.:.     .:|.:|..|    :|:|||.||||   |
Yeast   226 -MDAESAGSGSAPFGVFTTESRRVWSNIRDYLFHADDCTNWRNLKL----IDSALFVVCLD---D 282

  Fly   333 GVFNENQQEPLLKHLLAGKAQ--------------------NRWFDKSISLLISADGTTAINFEH 377
            ..|..:||:.|.:.:|.|.:.                    |||:|| :.|:::.:|...|||||
Yeast   283 VAFAADQQDELTRSMLCGTSTINLDPHQHQPPLNVQTGTCLNRWYDK-LQLIVTKNGKAGINFEH 346

  Fly   378 SWGDGVAVLRYFNELYKDTLKQPFVSTETVHTPAEGDFSNVRPINFEIDD---ATKSAVSEAYNK 439
            :..||..|||...::|          |:::.:.|.|...||..| |..||   ::.|..|.|::.
Yeast   347 TGVDGHTVLRLATDIY----------TDSILSFARGVTKNVVDI-FSDDDGKPSSSSLASAAHSA 400

  Fly   440 NASIV--------DNLDMNVL------------KYPHINKPTCKQYG---------LSPDSIIQL 475
            |...:        ||...:.|            :|..:|. ....||         .|||:.:|.
Yeast   401 NLITIPRKLEWRTDNFLQSSLHFAETRISDLISQYEFVNL-DFSNYGASHIKTVFKCSPDAFVQQ 464

  Fly   476 SFQLAYRQAYSGYVGSYESCSTSAFRHGRTETMRPCTNATRDFCEAILQPERSKPSAGELRAMID 540
            .||:||...|..:...||...|.||::||||.:|..|..::.|.:::|..:.|  .|.:::.:.|
Yeast   465 VFQVAYFALYGRFETVYEPAMTKAFQNGRTEAIRSVTGQSKLFVKSLLDQDAS--DATKIQLLHD 527

  Fly   541 NCSKVHGQLTKEAAMGQGFDRHLFALR---HTAQKEGIPIPDLYETEAYKRINNNIISTSTLGSD 602
            .|: .|.|:|:|.:.|.|.||||:||.   :...|:.:.:|.::..:::..:.||::|||..|:.
Yeast   528 ACT-AHSQITRECSQGLGQDRHLYALYCLWNQWYKDKLELPPIFRDKSWTTMQNNVLSTSNCGNP 591

  Fly   603 ALLAGSFGPVVKNGFGIGYSIQNDFAGAIVTTYKNQADGKVFIDSLESAFDKICAVI--QQSSSS 665
            .|.:..||||..|||||||.|::.....:|::...|.  ..|...:|.:..:|..:.  ||:.::
Yeast   592 CLKSFGFGPVTANGFGIGYIIRDHSVSVVVSSRHRQT--ARFASLMEKSLLEIDRIFKRQQARAA 654

  Fly   666 K 666
            |
Yeast   655 K 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_647756.1	Carn_acyltransf	45..655	CDD:279140	206/700 (29%)
YAT1	NP_009420.1	Carn_acyltransf	4..642	CDD:395612	206/700 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346192
Domainoid	1	1.000	236	1.000	Domainoid score	I388
eggNOG	1	0.900	-	-		E1_KOG3719
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H77
Inparanoid	1	1.050	236	1.000	Inparanoid score	I704
Isobase	1	0.950	-	0	Normalized mean entropy	S1588
OMA	1	1.010	-	-		QHG56597
OrthoFinder	1	1.000	-	-		FOG0006491
OrthoInspector	1	1.000	-	-		oto100281
orthoMCL	1	0.900	-	-		OOG6_104379
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2057
SonicParanoid	1	1.000	-	-		X4735
TreeFam	0	0.000	Not matched by this tool.
	14	13.680