DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CPT2 and cpt1b

DIOPT Version :9

Sequence 1:	NP_647756.1	Gene:	CPT2 / 38355	FlyBaseID:	FBgn0035383	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	XP_012822209.2	Gene:	cpt1b / 780223	XenbaseID:	XB-GENE-5931920	Length:	809	Species:	Xenopus tropicalis

Alignment Length:	632	Identity:	186/632 - (29%)
Similarity:	295/632 - (46%)	Gaps:	84/632 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LQCSKLPTLY-FQRSLPRLPIPLLENSCRRFLEATKPLLSPAEQAQTQQTVEQFRQGIGMEL--H 92
            :..|:.|.|| ||.|||:||:|.||::..|:|::.:|||...:.::.:...|:|::.:|.:|  :
Frog   194 IMSSRQPMLYSFQMSLPKLPVPPLEDTIERYLQSVRPLLDDDKFSEMKILAEEFQKDLGRKLQKY 258

  Fly    93 AKLKSHDAENKHTSYISQPWFD-MYLADRAPLPLNYNPLLVMKSDARPEYQQQVVRATNLIISSL 156
            ..|||..|.|    |:|..|.: :||..|.|:.:|.|...:......|. ..|..||.|:|.:.|
Frog   259 LHLKSWWALN----YVSDWWEEYIYLRGRGPIMVNSNYYAMDYLYVTPS-TNQAARAGNVIHAML 318

  Fly   157 RFWRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAPKAFATYASYAFKAFPLDMSQYNRLFGTSR 221
            .:.|.|:..|:.|.:                              |....|:..:|..|:|.|:|
Frog   319 LYRRKLERGLIPPVM------------------------------ALGIVPMCSNQMVRMFNTTR 353

  Fly   222 IPRIGKDELVQSPDAKHILVMRRGHMYAVNVLDSSGYIESPSVILGRLRAVLKLDADREAASVPL 286
            :|.:..|.|....:::|:.|..:|..|.: .|..:|.:.:|..:..:::.:|...:..:.....|
Frog   354 VPGVETDCLQHLVESRHVCVYHKGRYYRL-ALYENGNLLTPRQLQSQIQYILDDSSPPQPGEEKL 417

  Fly   287 GVLTSGQRDEWAKTRQHFVSNTKNADLLEREVDAALFCVCLDGEEDGVFNENQQEPL---LKHLL 348
            ..||:|.|..||:.|.:|.||..|...|.. |:.|:|.:.||.||.| :||..:..|   .|.||
Frog   418 AALTAGNRVHWAQARTNFFSNGINRTALSC-VERAVFFISLDEEEAG-YNEEDKSSLSAYSKALL 480

  Fly   349 AGKAQNRWFDKSISLLISADGTTAINFEHSWGDGVAVLRYFNELYKDTLKQP-FVSTETVHTPAE 412
            .|...|||||||.||::..:|...:|.||||.|...:    ..|::.||... |....|......
Frog   481 HGNCYNRWFDKSFSLVVFRNGKLGLNAEHSWADAPII----GHLWEFTLATDCFELGYTEDGNCR 541

  Fly   413 GDFSNVRP----INFEIDDATKSAVSEAYNKNASIVDNLDMNVLKYPHINKPTCKQYGLSPDSII 473
            ||..:..|    :.::|....:..:..:|....:|.|::|.:.|.:....|...|:...|||:..
Frog   542 GDAGSPLPPPYRLQWDIPPKCREVIERSYVTAKAIADDVDFHCLCFSDFGKGLIKKCRSSPDAFF 606

  Fly   474 QLSFQLAYRQAYSGYVGSYESCSTSAFRHGRTETMRPCTNATRDFCEAILQPERSKPSAGELRAM 538
            |::.|||:.:....:..:||:..|..||.|||||:|.||..|.||.:|:..|.:|:    |.|..
Frog   607 QIALQLAHYREKGHFCLTYEASMTRLFRDGRTETVRSCTTQTCDFVKAMEDPTQSQ----EKRLA 667

  Fly   539 IDNCSKVHGQLTKEAAM-GQGFDRHLFALRHTAQKEGIPIPDLYE--TEAYKRINNNIISTSTLG 600
            :...:..|.||....|| |:|.|||||.|...::..|.....|.:  :|.::      :|||...
Frog   668 LYRAAAEHHQLMYRWAMTGKGIDRHLFCLYIVSKYLGTDSAFLQKVLSEPWR------LSTSQTP 726

  Fly   601 SDAL-------------LAGSFGPVVKNGFGIGYSIQNDFAGAIVTT 634
            ...|             ..|.||||..:|:|:.|.    |||..:.|
Frog   727 QQQLKLFDLDKFPDHVSAGGGFGPVADDGYGVSYI----FAGENLIT 769

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_647756.1	Carn_acyltransf	45..655	CDD:279140	179/617 (29%)
cpt1b	XP_012822209.2	CPT_N	39..85	CDD:406797
cpt1b	XP_012822209.2	Carn_acyltransf	209..797	CDD:395612	179/617 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D559299at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010