Protein Alignment CPT2 and Crot

DIOPT Version :10

• Sequence 1: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_076222.1
• Gene: Crot / 74114
• MGIID: 1921364
• Length: 612
• Species: Mus musculus
• Alignment Length: 646
• Identity: 178/646 - (27%)
• Similarity: 306/646 - (47%)
• Gaps: 89/646 - (13%)

  Fly    38 TLYFQRSLPRLPIPLLENSCRRFLEATKPLLSPAEQAQTQQTVEQFRQGIGMELHAKLKSHDAEN 102
            |..:|.|||.||:|.||.|.:::||:.||..:..|..:|::.|::|::|.|..||.||... |..
Mouse    13 TFQYQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQEGAGKRLHQKLLER-ARG 76

  Fly   103 KHTSYISQPWFDM-YLADRAPLPLNYN---PLLVMKSDARPEYQQ--------QVVRATNLIISS 155
            |. :::.:.|.:: ||..|.|..||.|   |.        |.::.        |:.|.:.::..:
Mouse    77 KR-NWLEEWWLNVAYLDVRIPSQLNVNFVGPC--------PHFEHYWPAREGTQLERGSMMLWHN 132

  Fly   156 LRFWRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAPKAFATYASYAFKAFPLDMSQYNRLFGTS 220
            |.:|:.|:.:.|...      |..:|                         ||||:|:..||.|.
Mouse   133 LNYWQLLRREKLPVH------KSGNT-------------------------PLDMNQFRMLFSTC 166

  Fly   221 RIPRIGKDELV-------QSPDAKHILVMRRGHMYAVNVLDSSGYIESPSVILGRLRAVLKLDAD 278
            ::|.|.:|.::       :.....||.|:.||..:..:|| ..|.:.:|..:|.:|..:.| ...
Mouse   167 KVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVL-HEGCLITPPELLRQLTYIHK-KCS 229

  Fly   279 REAASVPLGVLTSGQRDEWAKTRQHFVS-NTKNADLLEREVDAALFCVCLDGEEDGVFNENQQEP 342
            .|.....:..|||.:|..|||.|::.:| :.:|..|||: :..:||...::........|...:
Mouse   230 NEPVGPSIAALTSEERTRWAKAREYLISLDPENLTLLEK-IQTSLFVYSIEDSSPHATPEEYSQ- 292

  Fly   343 LLKHLLAGKAQNRWFDKSISLLISADGTTAINFEHSWGDG---VAVLRYFNELYKDTLKQPFVST 404
            :.:.||.|....||.|||.:|:..|:|......:|:..|.   |.:..|.:|...:| :..:..:
Mouse   293 VFEMLLGGDPSVRWGDKSYNLISFANGIFGCCCDHAPYDAMVMVNIAHYVDERVLET-EGRWKGS 356

  Fly   405 ETVHTPAEGDFSNVRPINFEIDDATKSAVSEAYNKNASIVDNLDMNVLKYPHINKPTCKQYGLSP 469
            |.|.     |......:.|.:|:...:.||:|..::.....:|.:....:....|...|:..|.|
Mouse   357 EKVR-----DIPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHP 416

  Fly   470 DSIIQLSFQLAYRQAYSGYVGSYESCSTSAFRHGRTETMRPCTNATRDFCEAILQPERSKPSAGE 534
            |:.|||:.||||.:.:......||:..|..|.||||||:|.||.....:|:::     ..|||..
Mouse   417 DTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSM-----QDPSASL 476

  Fly   535 L---RAMIDNCSKVHGQLTKEAAMGQGFDRHLFALRHTAQKEGIPIPDLYETEAYKRI---NNNI 593
            |   :.|::..:| |.::.|:.:.|:||||||..|...|::||:|:|:|:|...:.|.   .|.:
Mouse   477 LERQQKMLEAFAK-HNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFV 540

  Fly   594 ISTSTLGSDALLAGSFGPVVKNGFGIGYSIQNDFAGAIVTTYKN--QADGKVFIDSLESAF 652
            :|||.:|. ..:.|...|:|.||:|..|.|::|......:::::  :.|.:..:..:..||
Mouse   541 LSTSLVGY-LRVQGVVVPMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIFHAF 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_647756.1	Carn_acyltransf	48..650	CDD:459926	171/632 (27%)
Crot	NP_076222.1	Carn_acyltransf	23..596	CDD:459926	171/630 (27%)
		Microbody targeting signal. /evidence=ECO:0000255	610..612