Protein Alignment CPT2 and CROT

DIOPT Version :9

• Sequence 1: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001137407.1
• Gene: CROT / 54677
• HGNCID: 2366
• Length: 640
• Species: Homo sapiens
• Alignment Length: 675
• Identity: 178/675 - (26%)
• Similarity: 315/675 - (46%)
• Gaps: 119/675 - (17%)

  Fly    38 TLYFQRSLPRLPIPLLENSCRRFLEA----------------------------TKPLLSPAEQA 74
            |..:|.|||.||:|.||.|.:::||:                            .||..:..|..
Human    13 TFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQVKPFANQEEYK 77

  Fly    75 QTQQTVEQFRQGIGMELHAKLKSHDAENKHTSYISQPWFDM-YLADRAPLPLNYN---PLLVMKS 135
            :|::.|::|:.|||.:||.||... |:.|. :::.:.|.:: ||..|.|..||.|   |....:.
Human    78 KTEEIVQKFQSGIGEKLHQKLLER-AKGKR-NWLEEWWLNVAYLDVRIPSQLNVNFAGPAAHFEH 140

  Fly   136 DARPEYQQQVVRATNLIISSLRFWRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAPKAFATYAS 200
            ...|:...|:.|.:..:..:|.:|:.|:.:.:...      |..:|
Human   141 YWPPKEGTQLERGSITLWHNLNYWQLLRKEKVPVH------KVGNT------------------- 180

  Fly   201 YAFKAFPLDMSQYNRLFGTSRIPRIGKDELV---------QSPDAKHILVMRRGHMYAVNVLDSS 256
                  ||||:|:..||.|.::|.|.:|.::         :||:  ||:|:.||..:..:|: ..
Human   181 ------PLDMNQFRMLFSTCKVPGITRDSIMNYFRTESEGRSPN--HIVVLCRGRAFVFDVI-HE 236

  Fly   257 GYIESPSVILGRLRAVLKLDADREAASVPLGVLTSGQRDEWAKTRQHFVS-NTKNADLLEREVDA 320
            |.:.:|..:|.:|..:.| ....|.....:..|||.:|..|||.|::.:. :.:|..|||: :.:
Human   237 GCLVTPPELLRQLTYIHK-KCHSEPDGPGIAALTSEERTRWAKAREYLIGLDPENLALLEK-IQS 299

  Fly   321 ALFCVCLDGEEDGVFNENQQEPLLKHLLAGKAQNRWFDKSISLLISADGTTAINFEHSWGDGVAV 385
            :|....::.....|..|:..| ::..:|.|....||.|||.:|:..::|....|.:|:..|.:.:
Human   300 SLLVYSMEDSSPHVTPEDYSE-IIAAILIGDPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIM 363

  Fly   386 LR---YFNE-LYKDTLKQPFVSTETVHTPAEGDFSNVRPINFEIDDATKSAVSEA---YNKNASI 443
            :.   |.:| ::::  :..:..:|.|.     |......:.|.:|:...:.:::|   |.:.||
Human   364 VNISYYVDEKIFQN--EGRWKGSEKVR-----DIPLPEELIFIVDEKVLNDINQAKAQYLREAS- 420

  Fly   444 VDNLDMNVLKYPHINKPTCKQYGLSPDSIIQLSFQLAYRQAYSGYVG-SYESCSTSAFRHGRTET 507
              :|.:....:....|...|...|.||:.|||:.||||.:.: |:.| .||:..|..|.||||||
Human   421 --DLQIAAYAFTSFGKKLTKNKMLHPDTFIQLALQLAYYRLH-GHPGCCYETAMTRHFYHGRTET 482

  Fly   508 MRPCTNATRDFCEAILQP-----ERSKPSAGELRAMIDNCSKVHGQLTKEAAMGQGFDRHLFALR 567
            ||.||.....:|:::..|     ||.       :.|:...:| |.::.|:.:.|:||||||..|.
Human   483 MRSCTVEAVRWCQSMQDPSVNLRERQ-------QKMLQAFAK-HNKMMKDCSAGKGFDRHLLGLL 539

  Fly   568 HTAQKEGIPIPDLYETEAYKRI---NNNIISTSTLGSDALLAGSFGPVVKNGFGIGYSIQNDFAG 629
            ..|::||:|:|:|:....:.:.   .|.::|||.:|. ..:.|...|:|.||:|..|.|::|...
Human   540 LIAKEEGLPVPELFTDPLFSKSGGGGNFVLSTSLVGY-LRVQGVVVPMVHNGYGFFYHIRDDRFV 603

  Fly   630 AIVTTYKN--QADGKVFIDSLESAF 652
            ...:.:|:  :.|.:..:.....||
Human   604 VACSAWKSCPETDAEKLVQLTFCAF 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_647756.1	Carn_acyltransf	45..655	CDD:279140	175/668 (26%)
CROT	NP_001137407.1	Carn_acyltransf	20..631	CDD:279140	175/668 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920