Protein Alignment CPT2 and cpt-6

DIOPT Version :10

• Sequence 1: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_504648.1
• Gene: cpt-6 / 179035
• WormBaseID: WBGene00020911
• Length: 746
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 173/660 - (26%)
• Similarity: 289/660 - (43%)
• Gaps: 111/660 - (16%)

  Fly    43 RSLPRLPIPLLENSCRRFLEATKPLLSPAEQAQTQQTVEQFRQGIGMEL--HAKLKSHDAENKHT 105
            |.||.||:|.|:::...:|::.|.:||..|.....:...:|.:..|.:|  :..:.|...:|
 Worm   146 RLLPSLPVPALKDTISEYLDSMKHILSEQEYEIVAKQAHEFLENEGKKLQRYTWIYSLFTDN--- 207

  Fly   106 SYISQPWFD-MYLADRAPLPLNYNPLLVMKSDARPEYQQQVVRATNLIISSLRFWRSLQADLLEP 169
             |::..|.. .||..|.||.:|                           ||:     ...|||..
 Worm   208 -YVTSFWQKYAYLHGRYPLMIN---------------------------SSV-----AHCDLLRD 239

  Fly   170 EVYHMNAKKSDTSSYRRWMKVAPKAFATYASYAFKAFPLDMSQYNRL-------------FGTSR 221
            :    .|.::..::...|::|            .....:|..||..|             :..:|
 Worm   240 K----EATRAHRAARVTWIEV------------MSHLAIDRQQYKALGDGLVCTRHYKNMYAVTR 288

  Fly   222 IPRIGKDELVQSPDAKHILVMRRGHMYAVNVLDSSGYIESPSVILGRLRAVLKLDADREAASVPL 286
            .|....|:|:.....|||:|:.||..|.::|:|....|.:...:......::..|...|.....:
 Worm   289 EPGKKIDQLILHGIQKHIVVVLRGKYYKIHVVDDKNNIYTVEQLTKIFHEMISRDEKEEGVIGKI 353

  Fly   287 GVLTSGQRDEWAKTRQ-HFVSNTKNADLLEREVDAALFCVCLDGEEDGVFNENQQEPL---LKHL 347
            ..||...||.|.:.|| :|:.|.|||.:| :|::.|:|...||..:|..::|.:.|.|   |.:.
 Worm   354 AALTHDTRDSWHRNRQKYFLGNVKNAQIL-KEIECAVFFFTLDENDDYGYDEKKPEVLSNFLANC 417

  Fly   348 LAGKAQNRWFDKSISLLISAD----GTTAINFEHSWGDGVA---VLRYFNELYKDTLKQPFV-ST 404
            |:|...|||.|||::.:.|.:    |||    |||..||..   ::..|..:..:.||...: ..
 Worm   418 LSGDGTNRWVDKSLNYICSKNARCGGTT----EHSIADGAEFDHIMENFVYVDLEVLKYKSIEEQ 478

  Fly   405 ETVHTPAEGDFSNVR---PINFEI-DDATKSAVSEAYNKNASIVDNLDMNVLKYPHINKPTCKQY 465
            |.:....|.|..:::   |:|||: |....|.::..|:.:....::||:..|.:....|...|:.
 Worm   479 EKMAVIEENDKKSLKLATPLNFEVPDQEMLSEITRCYDAHQIAKNDLDLYALAFRDFGKGRIKKC 543

  Fly   466 GLSPDSIIQLSFQLAYRQAYSGYVGSYESCSTSAFRHGRTETMRPCTNATRDFCEAILQPERSKP 530
            |:|||:.||::.|||..:....:|.:||..|...|.:.||||:|...:.:.:|.||:|....:|.
 Worm   544 GVSPDAFIQMAIQLANYRDQGKFVLTYEPASARFFANSRTETLRTVNDHSCEFVEAMLNANETKE 608

  Fly   531 SAGELRAMIDNCSKVHGQLTKEAAMGQGFDRHLFALRHTAQKEGI--PIPDLYETEAYKRINNNI 593
            :.   .|::....:.|....|:..:|||.|||||.|...:|..||  |..|.|..:.:|...:::
 Worm   609 AK---IALLKKACETHVLRNKKCMVGQGVDRHLFVLYILSQGTGIQSPFLDNYINQKWKLSTSHV 670

  Fly   594 ISTS------TLGSDALLAGSFGPVVKNGFGIGYSIQNDFAG-----AIVTTYKNQA--DGKVFI 645
            .:.:      |...:..|...||.|..:|:||.|.    |.|     |.:|:|.:.|  |...|.
 Worm   671 PNVTNQCDEDTDSDNTWLGACFGAVAADGYGICYR----FGGNHGIFANITSYHSAANTDSTKFA 731

  Fly   646 DSLESAFDKI 655
            ..|..:|.::
 Worm   732 KLLSESFHEL 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_647756.1	Carn_acyltransf	48..650	CDD:459926	169/648 (26%)
cpt-6	NP_504648.1	Carn_acyltransf	151..736	CDD:459926	169/648 (26%)