Protein Alignment CPT2 and Crat

DIOPT Version :10

• Sequence 1: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001407005.1
• Gene: Crat / 12908
• MGIID: 109501
• Length: 631
• Species: Mus musculus
• Alignment Length: 652
• Identity: 169/652 - (25%)
• Similarity: 296/652 - (45%)
• Gaps: 80/652 - (12%)

  Fly    42 QRSLPRLPIPLLENSCRRFLEATKPLLSPAEQAQTQQTVEQFRQ--GIGMELHAKLKSHDAENKH 104
            |.:|||||:|.|:.|...:|:|.:|::|..|.|.|:|.|::|:.  |:|..|...|:..  ..|.
Mouse    32 QDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLERR--AKKM 94

  Fly   105 TSYISQPWF-DMYLADRAPLPLNYNPLLVMKSDARPEYQQQVVRATNLIISSLRFWRSLQADLLE 168
            .:::|:.|. ..||..|.|:.:..:|.:::......:.|.|:..|..||...|.|...:..:.|.
Mouse    95 ENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDFKSMIDNETLP 159

  Fly   169 PEVYHMNAKKSDTSSYRRWMKVAPKAFATYASYAFKAFPLDMSQYNRLFGTSRIPRIGKDELVQS 233
            .|.                               ....||.|:||.::..:.|:|...:|.:|..
Mouse   160 VEF-------------------------------LGGQPLCMNQYYQILSSCRVPGPKQDSVVNF 193

  Fly   234 PDAK----HILVMRRGHMYAVNVLDSSGYIESPSVILGRLRAV--LKLDADREAASVPLGVLTSG 292
            ..:|    ||.|:.....:.::|..|.|...:...|..:|..:  ..|.:::|    |:|:|||.
Mouse   194 LKSKRPPTHITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKE----PVGILTSN 254

  Fly   293 QRDEWAKTRQHFVSNTKNADLLEREVDAALFCVCLDGEEDGVFNENQQEPLLKHLLAG-----KA 352
            .|:.|||...:.:.:..|.:.: ..:..::|.||||.:...|.::..:..:...:|.|     .:
Mouse   255 HRNTWAKAYNNLIKDKVNRESV-NSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNS 318

  Fly   353 QNRWFDKSISLLISADGTTAINFEHSWGDGVAVLRYFNELYKDTLKQPFVSTETVHTPAEGDFSN 417
            .||||||::..:::.||:..:.:||:..:|..::...:.:.:.|.|...|.:..|..|..
Mouse   319 GNRWFDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMP----- 378

  Fly   418 VRPINFEIDDATKSAVSEAYNKNASIVDNLDMNVLKYPHINKPTCKQYGLSPDSIIQLSFQLAYR 482
             :.:.|.|....|:.:.:|....:.::.:||:.:|.:.|..|...|...||||:.||::.||||.
Mouse   379 -KKLRFNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYY 442

  Fly   483 QAYSGYVGSYESCSTSAFRHGRTETMRPCTNATRDFCEAI---LQPERSKPSAGEL--------R 536
            :.|.....:|||.|...|..|||:|:|..:..:..|.:.:   ..||:.|.   ||        |
Mouse   443 RIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKV---ELLRKAVQAHR 504

  Fly   537 AMIDNCSKVHGQLTKEAAMGQGFDRHLFALRHTAQKEGIPIPDLYETEAYKRINNNIISTSTLGS 601
            |..|..|  |.|    |..|:.|||||..|:..|.::.:.:||::...:|....:..:|||.:.:
Mouse   505 AYTDRIS--HPQ----AIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPA 563

  Fly   602 DALLAGSFGPVVKNGFGIGYSIQNDFAGAIVTTYKNQADGKV--FIDSLESAFDKICAVIQQSSS 664
            .......|||||.:|:||.|:.........|:.|.:.|:...  ....||.|...:..::|....
Mouse   564 KTDCVMFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPR 628

  Fly   665 SK 666
            :|
Mouse   629 AK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_647756.1	Carn_acyltransf	48..650	CDD:459926	161/628 (26%)
Crat	NP_001407005.1	Carn_acyltransf	38..614	CDD:459926	161/628 (26%)
		Microbody targeting signal. /evidence=ECO:0000255	629..631		1/2 (50%)