Protein Alignment CPT2 and Cpt2

DIOPT Version :10

• Sequence 1: NP_647756.1
• Gene: CPT2 / 38355
• FlyBaseID: FBgn0035383
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_034079.2
• Gene: Cpt2 / 12896
• MGIID: 109176
• Length: 658
• Species: Mus musculus
• Alignment Length: 632
• Identity: 289/632 - (45%)
• Similarity: 419/632 - (66%)
• Gaps: 18/632 - (2%)

  Fly    29 QYLQCSKLPTLYFQRSLPRLPIPLLENSCRRFLEATKPLLSPAEQAQTQQTVEQFRQGIGMELHA 93
            :|||.|.:||:::|.||||||||.||::.:|:|.|.||||:.::..:|:...:.|..|||.||||
Mouse    33 EYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLSAQKPLLNDSQFRKTEVLCKDFENGIGKELHA 97

  Fly    94 KLKSHDAENKHTSYISQPWFDMYLADRAPLPLNYNPLLVMKSDARPEYQQQVVRATNLIISSLRF 158
            .|.:.|.:||||||||.|||||||..|..:.||:||.:....|.:.||..|:.|||||.:|::||
Mouse    98 HLLAQDKQNKHTSYISGPWFDMYLTARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRF 162

  Fly   159 WRSLQADLLEPEVYHMNAKKSDTSSYRRWMKVAPKAFATYASYAFKAFPLDMSQYNRLFGTSRIP 223
            .::|:|.||||||:|:|..:|||.:::|.::..|.:.:.|.:|...|:|||||||.|||.::|||
Mouse   163 LKTLRAGLLEPEVFHLNPARSDTDAFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRIP 227

  Fly   224 RIGKDELVQSPDAKHILVMRRGHMYAVNVLDSSGYIESPSVILGRLRAVLKLDADREAASVPLGV 288
            :..:|||.....|:|:||:|:||.|..:|||..|.|.:||.|...|:.:|. |:. .....||..
Mouse   228 KPSRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNPSEIQAHLKYILS-DSS-PVPEFPLAY 290

  Fly   289 LTSGQRDEWAKTRQHFVSNTKNADLLEREVDAALFCVCLDGEEDGVFNENQQEPLLKHLLAGKAQ 353
            |||..||.||:.||..:.......|  |:||:|:||:|||.     |.......|...:|.|...
Mouse   291 LTSENRDVWAELRQKLIHGGNEETL--RKVDSAVFCLCLDD-----FPMKDLVHLSHTMLHGDGT 348

  Fly   354 NRWFDKSISLLISADGTTAINFEHSWGDGVAVLRYFNELYKDTLKQPFVSTETVHTPAEGDFS-N 417
            |||||||.:|:::.|||.|::|||:|||||||||:|||:::|:.:.|.::.::  .||..|.| :
Mouse   349 NRWFDKSFNLIVAKDGTAAVHFEHAWGDGVAVLRFFNEVFRDSTQTPAIAPQS--QPAATDSSVS 411

  Fly   418 VRPINFEIDDATKSAVSEAYNKNASIVDNLDMNVLKYPHINKPTCKQYGLSPDSIIQLSFQLAYR 482
            |:.::|::..|.|:.|:.|..|..:.:..|.::.:::....|...|:..||||::.||:||:|:.
Mouse   412 VQKLSFKLSSALKAGVTAAKEKFDATMKTLTIDAIQFQRGGKEFLKKKKLSPDAVAQLAFQMAFL 476

  Fly   483 QAYSGYVGSYESCSTSAFRHGRTETMRPCTNATRDFCEAILQPERSKPSAGELRAMIDNCSKVHG 547
            :.|...|.:||||||:||:||||||:||.:..|:...||.:: |.||.|.|||:.|:..|||.||
Mouse   477 RQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVR-EPSKHSVGELQHMMAECSKYHG 540

  Fly   548 QLTKEAAMGQGFDRHLFALRHTAQKEGIPIPDLYETEAYKRINNNIISTSTLGSDALLAGSFGPV 612
            ||||||||||||||||||||:.|...|:.:|:||:..||:|||:||:|||||.|.|:..|.|.||
Mouse   541 QLTKEAAMGQGFDRHLFALRYLAAARGVTLPELYQDPAYQRINHNILSTSTLSSPAVSLGGFAPV 605

  Fly   613 VKNGFGIGYSIQNDFAGAIVTTYKNQADGKVFI----DSLESAFDKI 655
            |.:||||.|::.:|:.|..|::|..: :.:.|:    ..||..||.:
Mouse   606 VPDGFGIAYAVHDDWIGCNVSSYSGR-NAREFLHCVQKCLEDMFDAL 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPT2	NP_647756.1	Carn_acyltransf	48..650	CDD:459926	275/606 (45%)
Cpt2	NP_034079.2	Carn_acyltransf	52..642	CDD:459926	274/602 (46%)