Protein Alignment Shab and kcna1a

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_005163101.1
• Gene: kcna1a / 795942
• ZFINID: ZDB-GENE-110408-15
• Length: 492
• Species: Danio rerio
• Alignment Length: 549
• Identity: 181/549 - (32%)
• Similarity: 273/549 - (49%)
• Gaps: 123/549 - (22%)

  Fly   308 RVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSIL 372
            ||.||:.|:|.|...:||.:.|.|.||..::...:         :....|||||||:..||.:||
Zfish    35 RVVINIAGLRFETQLKTLAQFPETLLGNPKKRMRY---------FDPLRNEYFFDRNRPSFDAIL 90

  Fly   373 NFYRT-GKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDE 436
            .:|:: |:|.....:.:..||::::::   ||.:|:  ..|:.:.:..:.||.|...|.
Zfish    91 YYYQSGGRLRRPANVPLDMFSEEIKFY---ELGVEA--MEKFREDEGFIREEERPLPEK------ 144

  Fly   437 EEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQH--------I 493
                     |:|:.:|.|.|.|.:|..||.||::|::.|::|.:...|.|||:|:.        |
Zfish   145 ---------EFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDPEGRIKII 200

  Fly   494 DNGTPQDNPQLA-----MVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSL- 552
            .|.|....|.:.     ::|.:||.||:.|.|:||.|.|.|..|||..:|.||::||:|||::|
Zfish   201 GNTTYYYKPSILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLG 265

  Fly   553 -FLLE--TNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFL 614
             .|.|  ..|....:......:::|.|::|:.||.||:|||.|||.||.||:.|.:|||||:.||
Zfish   266 TELAEEQDGKEGKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFL 330

  Fly   615 AMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVL 679
            .:||::|||..||||.:||::.|.|||:.||||.::||||||||:.|.|..||::|::|.|.|||
Zfish   331 FIGVILFSSAVYFAEAEEKESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVL 395

  Fly   680 VIALPIPIIVNNFAEFYKNQMRREKALKRREALDRAKREGSIVSFHHINLKDAFAKSMDLIDVIV 744
            .||||:|:||:||..||..:...|                               :...|::|
Zfish   396 TIALPVPVIVSNFNYFYHRETEGE-------------------------------EQAQLLNV-- 427

  Fly   745 DTGKQTNVVHPKGKRQSTPNIGRQTLDVQSAPGHNLSQTDGNSTEGESTSGRNPATTGTGCYKNY 809
                            |.|||.                :|.||      |.|:.:|.....|...
Zfish   428 ----------------SNPNIA----------------SDSNS------SRRSSSTVSKSEYMEI 454

  Fly   810 D-----HVANLRNSNLHNRRGSSSEQDAV 833
            |     .:.|.|.:||.....:...|:.|
Zfish   455 DGDINNSIDNFREANLRTGNCTIPNQNCV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	33/106 (31%)
		Ion_trans	464..700	CDD:459842	116/252 (46%)
kcna1a	XP_005163101.1	BTB_POZ	34..160	CDD:453885	43/153 (28%)
		Ion_trans	163..415	CDD:459842	116/251 (46%)