Protein Alignment Shab and kcnv2a

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001373570.1
• Gene: kcnv2a / 567267
• ZFINID: ZDB-GENE-091117-27
• Length: 518
• Species: Danio rerio
• Alignment Length: 436
• Identity: 169/436 - (38%)
• Similarity: 266/436 - (61%)
• Gaps: 24/436 - (5%)

  Fly   302 SKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPK 366
            |...|..::|||||..:::.:|...:.|.||:|||...|.|...::|||||::.:||:||||.|.
Zfish    77 SPVKNYMLNINVGGKVYQISYRVAAKYPKTRIGRLATYTDHNRKLDLCDDYTVHNNEFFFDRDPD 141

  Fly   367 SFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMR----KE 427
            .|.:|.||||||.|.|.||:|...|.:::.||||.......||:..:.:|::.::|:::    .|
Zfish   142 VFHNIFNFYRTGVLWIKDELCPRNFLEEINYWGVRIKNTHRCCRISFEERQDELNEQLKVQRELE 206

  Fly   428 AESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQH 492
            ||...:..|:.|.:......:..:|.::|||.:|..|:::||.|..|:::|.:|:||||:.::|:
Zfish   207 AEVETEEHEDLFQDMAFGHTRFLIWNMMEKPFSSIIAKIMAVASSFFVLVSLVAMTLNTVEEMQY 271

  Fly   493 I-DNGTPQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFL-- 554
            | .||..........||..||.:||:||:||..::||..:|.:..||.:||:||||.::.:.|
Zfish   272 ITTNGQLSGKTYCEYVETFCIAFFTMEYLLRLVSTPDLTRFGRSVLNAVDLIAILPLYLQMVLES 336

  Fly   555 LETN---KNATDQFQDVRR------VVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLL 610
            .|::   |:.:| .:.|.|      |:::.|:|||.||||||||||||::.|||||..|:::|.|
Zfish   337 FESHDYWKHGSD-IETVGRVGKLGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCL 400

  Fly   611 MLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCI 675
            .||:|||:|.||::.|..|.|...|.|.|||..:|||.::::||||||::|.|.||::....|..
Zfish   401 FLFIAMGILTFSAMVYTVEHDVHKTNFTSIPHAWWWAAVSISTVGYGDMFPETHLGRIFAFACIS 465

  Fly   676 CGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREALDRAKREGSI 721
            .|:::..:||.|:.|.|:::|..       ||..|.....|..|.:
Zfish   466 FGIILNGMPISILFNKFSDYYSK-------LKAYEYTSSIKNRGKV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	47/107 (44%)
		Ion_trans	464..700	CDD:459842	104/247 (42%)
kcnv2a	NP_001373570.1	BTB_POZ_KCNV2	84..191	CDD:349732	46/106 (43%)
		Ion_trans	243..490	CDD:459842	104/254 (41%)