DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shab and kcng3

DIOPT Version :9

Sequence 1:	NP_001189037.1	Gene:	Shab / 38352	FlyBaseID:	FBgn0262593	Length:	1607	Species:	Drosophila melanogaster
Sequence 2:	XP_021336001.1	Gene:	kcng3 / 565643	ZFINID:	ZDB-GENE-111111-9	Length:	422	Species:	Danio rerio

Alignment Length:	416	Identity:	161/416 - (38%)
Similarity:	253/416 - (60%)	Gaps:	30/416 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 INVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFY 375
            :||||.::......::..|..|:.||..|::.:.::|:||||....||:|||||.::|..|:.:.
Zfish    10 LNVGGTKYAFTREVIKDFPLRRVSRLHSCSSEKEVLEVCDDYDRERNEFFFDRHSEAFVFIMLYV 74

  Fly   376 RTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVH-----EEMRKEAESLRQRD 435
            |:|||..|.:||.|:|.:::.|||::..:||.|||.:...|..:.:     ::|:.|.||   |.
Zfish    75 RSGKLRFVPQMCELSFYNEMIYWGLESSHLEFCCQRRLEDRMSDTYTYFSEDDMKAEVES---RG 136

  Fly   436 EEE----FGEGK-CAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHIDN 495
            |||    |...: .|.:.:.:....|:|.:|.||:::|.:|::|:::|.:.|..:|||......|
Zfish   137 EEEQVSRFAPDRGSARWLERMRRTFEEPASSIAAQILASVSVVFVIMSMVILCASTLPDWDTAKN 201

  Fly   496 GTPQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLE-TNK 559
            .|.:::   .::|||||.|||.|.|:||..|.||.:|.:..|||||||||.||:||:.:.. |.:
Zfish   202 NTVEEH---RIIEAVCIGWFTAECIVRFIVSRDKCEFVRRPLNIIDLLAITPYYVSVAMTALTGE 263

  Fly   560 NATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSL 624
            |  .|.|.....::|.|:|||..::|||||..|||:||.|||..|:|:.:|::|:.:.:.|||:|
Zfish   264 N--PQLQRAGVTLRVLRMMRIFWLIKLARHFLGLQTLGLTLRRCYREMVMLLVFVCVAMAIFSAL 326

  Fly   625 AYFAEK----DEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPI 685
            |...|.    :..:..:.|||.:.||..|:||||||||:||.|..|:|:|.||.:.|::::||||
Zfish   327 AQLLEHGLDLETSNEDYASIPASCWWVIISMTTVGYGDMYPITIPGRVLGGVCVVSGIVLLALPI 391

  Fly   686 PIIVNNFAEFYKNQMRREKALKRREA 711
            ..|.::|.:.|..       ||.|.|
Zfish   392 TFIYHSFVQCYHE-------LKFRSA 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	40/104 (38%)
		BTB_2	309..408	CDD:280393	37/96 (39%)
		Ion_trans	501..700	CDD:278921	91/203 (45%)
		Ion_trans_2	613..696	CDD:285168	36/86 (42%)
kcng3	XP_021336001.1	BTB	9..107	CDD:321966	37/96 (39%)
kcng3	XP_021336001.1	Ion_trans	170..406	CDD:306908	102/247 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.020