Protein Alignment Shab and kcna2b

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001104640.1
• Gene: kcna2b / 562853
• ZFINID: ZDB-GENE-080204-89
• Length: 495
• Species: Danio rerio
• Alignment Length: 523
• Identity: 180/523 - (34%)
• Similarity: 275/523 - (52%)
• Gaps: 101/523 - (19%)

  Fly   263 SISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLER 327
            :::.|.|....:...|..|.|:.        |||     ......||.||:.|:|.|...:||.:
Zfish     2 TVATGDPADEAAALPGQPQDTYD--------PEP-----DHECCERVVINISGLRFETQLKTLSQ 53

  Fly   328 LPHTRLG----RLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRT-GKLHIVDEMC 387
            .|.|.||    |:|.             :....|||||||:..||.:||.:|:: |:|.....:.
Zfish    54 FPETLLGDPKKRMRY-------------FDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVT 105

  Fly   388 VLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLW 452
            :..||:::.::.:.|..:                 ||.:|.|...:.:|:...|.   |:|:.:|
Zfish   106 LDIFSEEIRFYELGEEAI-----------------EMFREDEGFIKEEEKLLPEN---EFQRQVW 150

  Fly   453 ELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHIDNG-----TPQDNPQLA------- 505
            .|.|.|.:|..||:||:||::.|::|.::..|.|||..::.:..     ....|..::
Zfish   151 LLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRNEETDMHKAYRTDSNSTISYTSTYFT 215

  Fly   506 ----MVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQ 566
                ::|.:||.||:.|:::||.|.|.|..||...:||||::||:|||::|. .|..:.|.|..|
Zfish   216 DPFFILETLCIIWFSFEFLVRFFACPSKAGFFVNIMNIIDIVAIIPYFITLG-TELAEKAEDGQQ 279

  Fly   567 DVR----RVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYF 627
            ..:    .:::|.|::|:.||.||:|||.|||.||.||:.|.:|||||:.||.:||::|||..||
Zfish   280 GQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYF 344

  Fly   628 AEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNF 692
            ||.||.|::|||||:.||||.::||||||||:.|||..||::|::|.|.|||.||||:|:||:||
Zfish   345 AEADEPDSQFVSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNF 409

  Fly   693 AEFYKNQMRREK-----------ALKRREALDRAKREGSIVS-----------------FHHINL 729
            ..||..:...|:           .:...|.|.:: |.||.:|                 |...|:
Zfish   410 NYFYHRETEGEEQAQYLNVTSVPKIDSSEDLKKS-RSGSTMSKSDYMEIQEAVNNSNEDFREENI 473

  Fly   730 KDA 732
            |.|
Zfish   474 KTA 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	32/112 (29%)
		Ion_trans	464..700	CDD:459842	116/255 (45%)
kcna2b	NP_001104640.1	BTB_POZ	33..159	CDD:453885	44/158 (28%)
		Ion_trans	162..416	CDD:459842	116/254 (46%)