Protein Alignment Shab and kcng4a

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001103499.1
• Gene: kcng4a / 561003
• ZFINID: ZDB-GENE-050419-11
• Length: 538
• Species: Danio rerio
• Alignment Length: 435
• Identity: 168/435 - (38%)
• Similarity: 259/435 - (59%)
• Gaps: 22/435 - (5%)

  Fly   311 INVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFY 375
            |||||.|:...|.|||:.|.||||||:.|::.|.|..:||||..|.:|:||||.|.:|..||||.
Zfish    63 INVGGNRYTFPWSTLEQFPLTRLGRLKPCSSPEEIARVCDDYDEARHEFFFDRSPNAFRVILNFL 127

  Fly   376 RTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRD---EE 437
            ..|||.::.|||.|:..::|.||||:..|:|.||:.|.:.|.|.|.|..|:| |..|||:   ..
Zfish   128 AAGKLRLLREMCALSLHEELNYWGVEMTYMERCCKRKMYTRLEEVAELERRE-EERRQRNLQLRP 191

  Fly   438 EFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHIDNG--TPQD 500
            ...|.:..::...|.:::|.|.:....:|.|..|:|.:.::.|:|.::|:|.|:..:|.  ..|.
Zfish   192 PIVETRYRKFMNQLRDMVENPQSGVPGKVFACFSVLMVAITVISLCISTMPDLREEENRGVCSQK 256

  Fly   501 NPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQ- 564
            ...:.::|.||:.||:||::|||..:..|.:|.:|.|||||.:|||||:|||.:.|...:..::
Zfish   257 CQHMFIIETVCVAWFSLEFLLRFVQARSKLQFLRGPLNIIDAMAILPYYVSLVVDEKPNDENERP 321

  Fly   565 ------FQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSS 623
                  ...:..|:::.|.:|||.:::|||||.|||:||.|:|.|.:|.|||:|||.:.|.:||.
Zfish   322 SGGKGYLDKLGLVLRILRALRILYVMRLARHSLGLQTLGLTVRRSTREFGLLLLFLCVAVTLFSP 386

  Fly   624 LAYFAEKDEKDTK-FVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPI 687
            |.:.||.:....: |.|||.::|||.|:||||||||:.|.:..|:|:.....:.|:|::|.|...
Zfish   387 LVHLAESELTGVQDFSSIPASYWWAIISMTTVGYGDMVPRSIPGQVVALSSILSGILIMAFPATS 451

  Fly   688 IVNNFAEFYKNQMRREKALKRREALDRA--------KREGSIVSF 724
            |.:.|:..|:...:....|.:.|....|        :::|..|:|
Zfish   452 IFHMFSRSYQELKQEHDRLFKEECAAAAAATTGLEEEQDGGWVAF 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	53/104 (51%)
		BTB_2	309..408	CDD:280393	50/96 (52%)
		Ion_trans	501..700	CDD:278921	84/206 (41%)
		Ion_trans_2	613..696	CDD:285168	33/83 (40%)
kcng4a	NP_001103499.1	BTB	63..169	CDD:197585	53/105 (50%)
		BTB_2	63..160	CDD:280393	50/96 (52%)
		Ion_trans	261..464	CDD:278921	84/202 (42%)
		Ion_trans_2	376..458	CDD:285168	33/81 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910