Protein Alignment Shab and kcnc3a

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_073797827.1
• Gene: kcnc3a / 559096
• ZFINID: ZDB-GENE-100901-1
• Length: 666
• Species: Danio rerio
• Alignment Length: 601
• Identity: 204/601 - (33%)
• Similarity: 296/601 - (49%)
• Gaps: 110/601 - (18%)

  Fly   306 NSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSS 370
            :.::.||.||:|||....||:.||.|||..|.|.......     ||....:|:||||||.:|:.
Zfish    35 SEKIVINCGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNF-----DYDPKSDEFFFDRHPNTFAF 94

  Fly   371 ILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAES----- 430
            |||:|||||||...::|...|.::|.:||:||..:|:||...|.|.::  .||.....|:
Zfish    95 ILNYYRTGKLHCPSDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRD--AEEALDSFETPEPDP 157

  Fly   431 --------------LRQRDEEEFGE--GKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLST 479
                          |::...:|.|.  .:.:.:|.::|.|.|.|.:|..||.:|..|:|||::|.
Zfish   158 PEDDPALTGGADGDLKRLCLQEDGRNPSRWSTWQPWVWALFEDPYSSKYARYVAFGSLLFILISI 222

  Fly   480 IALTLNTLPQLQHIDNGTPQ-----------------DNPQLAMVEAVCITWFTLEYILRFSASP 527
            ....|.|......|.|.|..                 || .|..||.||:.|||:|...|....|
Zfish   223 STFCLETHEAFNTIYNKTENVTVGNVTREEVVFEVVTDN-WLTYVEGVCVVWFTIEVFTRVIFCP 286

  Fly   528 DKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTG 592
            ||.:|||..|||||.:||||:::.:.|...:..|.   :||...::|.|.:|||||.||.||..|
Zfish   287 DKAEFFKSSLNIIDFVAILPFYLEMALSGLSSKAA---KDVLGFLRVVRFVRILRIFKLTRHFVG 348

  Fly   593 LQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEK---DEKD------TKFVSIPETFWWAG 648
            |:.||.|||.|..|..||::|||:|||||:::.|:||:   |..|      |.|.:||..||||.
Zfish   349 LRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDPTASAHTAFKNIPIGFWWAV 413

  Fly   649 ITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRR-EAL 712
            :||||:||||:||.|..|.::|.:|.:.|||.||:|:|:|||||..:|...|.::|..|:: :.:
Zfish   414 VTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHI 478

  Fly   713 DRAKREGS------------IVSFHHI--NLKDAFAKSMDLI-------DVIVDTGKQTNVVHPK 756
            .||.:.||            ..|.|.|  |:..:...|..:.       :.|::..:..:..:..
Zfish   479 PRAPQPGSPNYCKPDALAMATASPHRIMGNVLGSMVVSGSMAGDCPLAQEEIIEINRADSKQNGD 543

  Fly   757 GKRQSTPNIGRQTLDVQSAPGHNLSQTDGNSTEGESTSGRNPAT----TGTGCYKNYDH------ 811
            ....:..|....|:|....|                 ..|:|||    |||| .:.|.|
Zfish   544 AANAALANEDCPTIDQVLGP-----------------DDRSPATGGLGTGTG-RERYPHDRACFL 590

  Fly   812 --VANLRNSNLHNRRG 825
              ....|.::.:.|:|
Zfish   591 LSTGEFRTTDSNVRKG 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	46/107 (43%)
		Ion_trans	464..700	CDD:459842	114/261 (44%)
kcnc3a	XP_073797827.1	None