Protein Alignment Shab and kcnf1a

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001076280.1
• Gene: kcnf1a / 557280
• ZFINID: ZDB-GENE-041001-217
• Length: 494
• Species: Danio rerio
• Alignment Length: 479
• Identity: 193/479 - (40%)
• Similarity: 284/479 - (59%)
• Gaps: 26/479 - (5%)

  Fly   307 SRVSINVGGVRHEVLWRTLERLPHTRLGRL--RECTTHEAIVELCDDYSLADNEYFFDRHPKSFS 369
            :.:|:|:|||:|.:....|.|.|.|||..|  |...:.|.:..|||||.....|::|||.||:|.
Zfish    21 TEISVNIGGVKHTLYGDVLNRYPETRLAELLNRVSDSAEDLSGLCDDYDDLKREFYFDRDPKAFK 85

  Fly   370 SILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQ- 433
            .||..|..|::|:...:|.:.|..:::|||:||.||:.||:...::    |..|:.:.||.::.
Zfish    86 CILELYYYGEIHMKRGICPMCFMKEMDYWGIDEDYLDECCRCSLNE----VETELAEIAEKVKTI 146

  Fly   434 ----RDEEEFGEGKCAEYQK---YLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQ 491
                .|:::..:.:.:..|:   :||:|:|||.:|.|||||||:|.:||:||::.:.:.|:|:||
Zfish   147 LDDLEDDDDDDDARVSRSQRCQTFLWKLMEKPESSVAARVIAVVSFVFILLSSVVMCVGTIPELQ 211

  Fly   492 -HIDNGTPQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLL 555
             ..|.|...::|.|..:|..||.|||:||:||.::|..|..|....|||||.|||:|::|.|.|.
Zfish   212 VQDDEGHLTEHPTLEAIETACIIWFTVEYVLRLASSSSKLHFVFSFLNIIDFLAIMPFYVVLILT 276

  Fly   556 ETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLI 620
            ... .|..:..:|::.||..|||||.||.||||||:|||:|.|.|::|.||||||::::::|:.:
Zfish   277 HLG-TAMMELANVQQAVQALRIMRIARIFKLARHSSGLQTLTFALKSSLKELGLLLMYMSVGIFL 340

  Fly   621 FSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPI 685
            ||:|.|..|:...:|.|.|||::||||.|||||||||||||.|.||:....|..:|||:.|||||
Zfish   341 FSALGYTMEQSHPETMFTSIPQSFWWAIITMTTVGYGDIYPKTTLGRCNAAVSFLCGVIAIALPI 405

  Fly   686 PIIVNNFAEFYKNQMRREKALK----------RREALDRAKREGSIVSFHHINLKDAFAKSMDLI 740
            ..|:|||...|..|...|.|.|          |.||.:..:.|....|....::.|:.|.|....
Zfish   406 HPIINNFVIVYSKQRVLETAAKHEIELMALRAREEAQECPEAERRAASVDSSSMWDSAAVSASQS 470

  Fly   741 DVIVDTGKQTNVVHPKGKRQSTPN 764
            |..:....:|..|....:.|...|
Zfish   471 DSFIPLLGETATVSKNQRAQKCNN 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	43/108 (40%)
		Ion_trans	464..700	CDD:459842	119/236 (50%)
kcnf1a	NP_001076280.1	BTB_POZ_Kv5_KCNF1	21..136	CDD:349690	44/118 (37%)
		Ion_trans	184..420	CDD:459842	119/236 (50%)