Protein Alignment Shab and kcna5

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_004912856.2
• Gene: kcna5 / 496997
• XenbaseID: XB-GENE-6037401
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 212/676 - (31%)
• Similarity: 313/676 - (46%)
• Gaps: 186/676 - (27%)

  Fly   193 GAGASVTGSGSGAGTGTGTGAGS-------------------------GSGSGAAGKEVRYAPFP 232
            ||..::.|:|..||:.......:                         |||.....::.:|.|
 Frog    11 GAAPALVGTGEDAGSAMAANTSTNRRDLLQIPRATSWLNDYSQGRQEEGSGESCQQQQQQYQP-- 73

  Fly   233 VASPTHSIPTTSQQIVGSVGGVGVGGASSQSISGGVPTHSQSN-----------------TTGAL 280
                    |.|     |..||.|..|       |||..|..||                 |...|
 Frog    74 --------PGT-----GQAGGGGCRG-------GGVGHHLPSNDMIMSHPGSTIKECDIETVIRL 118

  Fly   281 --QRTHSRSMSSIPPPEP--------FMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLG- 334
              :..|::..|...|.|.        .|..:|   |.||.||:.|:|.|....||.:.|.|.||
 Frog   119 EEEEPHAQQHSHHHPEEEEDHQFDLGIMDHES---NQRVIINIAGLRFETQLSTLNQFPDTLLGD 180

  Fly   335 ---RLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRT-GKLHIVDEMCVLAFSDDL 395
               |:|             .:....|||||||:..||..||.||:: ||:.....:.:..|:|::
 Frog   181 PEKRMR-------------FFDPLRNEYFFDRNRPSFDGILYFYQSGGKIRRPVNVSIDVFADEI 232

  Fly   396 EYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEF--GEGK---CAEYQKYLWELL 455
            .::.:.|..:|                         |.|::|.|  .|.|   |.|:|:.:|.:.
 Frog   233 RFYELGEEAME-------------------------RFREDEGFIKDEEKPLPCNEFQRQVWLIF 272

  Fly   456 EKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHIDNGTP----------QDNPQ------- 503
            |.|.:|.:||.||::|:|.|::|.|...|.|||:.:. :|..|          |::|.
 Frog   273 EYPESSSSARGIAIVSVLVILISIITFCLETLPEFRD-ENELPPALSKVLNDTQEHPSPPSGLTD 336

  Fly   504 -LAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQD 567
             ..::|..|:.|||.|.::||.|.|.|..|.|..:||||::||:|||::|. .|..::.|:..|.
 Frog   337 PFFIIETTCVIWFTFELLVRFFACPSKSDFSKNIMNIIDIVAIIPYFITLG-TELAQHQTNNGQQ 400

  Fly   568 VR--RVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEK 630
            ..  .:::|.|::|:.||.||:|||.|||.||.||:.|.:|||||:.||.:||::|||..||||.
 Frog   401 AMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEA 465

  Fly   631 DEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEF 695
            |:.::.|.|||:.||||.:|||||||||:.|.|..||::|::|.|.|||.||||:|:||:||..|
 Frog   466 DDPESHFSSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYF 530

  Fly   696 YKNQMRREKALKRREALDRAKREGSIV-----------------------------SFHHINLKD 731
            |..:...|:.:..:|  :.:.|:||..                             |....|||
 Frog   531 YHRETDHEEQVMLKE--ESSSRQGSCAGDLKRSPSRASLSKSVHLENIEGINNGTGSLEKTNLK- 592

  Fly   732 AFAKS-----MDLIDVIVDTGKQTNV 752
              |||     ..|..:.:||.::|::
 Frog   593 --AKSNVDLRKSLYALCLDTNRETDL 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	35/112 (31%)
		Ion_trans	464..700	CDD:459842	116/255 (45%)
kcna5	XP_004912856.2	BTB_POZ	152..278	CDD:453885	46/163 (28%)
		Ion_trans	281..534	CDD:459842	116/254 (46%)