Protein Alignment Shab and Shal

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Alignment Length: 575
• Identity: 183/575 - (31%)
• Similarity: 278/575 - (48%)
• Gaps: 95/575 - (16%)

  Fly   293 PPEPFMIAQSKAVNSRVSINVGGVRHEVLWR-TLERLPHTRLGRLRECTTHEAIVELCDDYSLAD 356
            ||.|....:.|..:.::.|||.|.|.|. || |||:.|.|.||.......::   |.|
  Fly    27 PPPPMPKDRRKTDDEKLLINVSGRRFET-WRNTLEKYPDTLLGSNEREFFYD---EDC------- 80

  Fly   357 NEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVH 421
            .||||||.|..|..|||:|||||||.....|:.::.::|.::|:....:..||...|..||
  Fly    81 KEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRK---- 141

  Fly   422 EEMRKEAESLRQRDEEEFGE---GKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALT 483
               |:.||.|......|.|:   .:....::.:|...|.|:||.:|.|...::..||.:|.:|..
  Fly   142 ---RENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANV 203

  Fly   484 LNTLPQLQHIDN--GTPQDNPQLAMV----EAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDL 542
            :.|:| ..|...  ||.....:..:|    :..|:..||.||:||..|:||:.||.:..::|||:
  Fly   204 VETVP-CGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDV 267

  Fly   543 LAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKEL 607
            :||:||::.|.:.:.:        ||.......|:.|:.||.|.:|||.||:.||:||::...||
  Fly   268 VAIMPYYIGLGITDND--------DVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASEL 324

  Fly   608 GLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTV 672
            |.|:..|||.::||:::.::|||:...|.|.|||..||:..:||||:||||:.|.|..||::|.|
  Fly   325 GFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGV 389

  Fly   673 CCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREA-------------------------- 711
            |.:.||||||||:|:||:||:..|....|.:|...:|:|
  Fly   390 CSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEAR 454

  Fly   712 ---------LDRAKREGSIVSFHHINLKDAFAKSMD--LIDVIVDTGKQTNVVHPKGKRQSTPNI 765
                     ||...|:..|....|.:|.....|:.|  .:::.:....|.       ||..:|:
  Fly   455 WAAQESGIELDDNYRDEDIFELQHHHLLRCLEKTTDREFVELEIPFNGQP-------KRPGSPS- 511

  Fly   766 GRQTLDVQSAPGHNLSQTDGNSTEG--ESTSGRNPATTGTGCYKNYDHVANLRNS 818
                  ..::|.|:.     ||..|  :|..||..:.....|.|.....:|.:||
  Fly   512 ------PMASPAHST-----NSAAGLLQSCCGRCCSQRYQACGKYMPAASNAQNS 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	40/108 (37%)
		Ion_trans	464..700	CDD:459842	96/241 (40%)
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	48/134 (36%)
		Ion_trans	188..415	CDD:459842	94/235 (40%)
		DUF3399	471..535	CDD:463381	17/82 (21%)