Protein Alignment Shab and Kcnf1

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_963289.2
• Gene: Kcnf1 / 382571
• MGIID: 2687399
• Length: 505
• Species: Mus musculus
• Alignment Length: 452
• Identity: 182/452 - (40%)
• Similarity: 275/452 - (60%)
• Gaps: 13/452 - (2%)

  Fly   274 SNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRE 338
            |...|::..:..:|:     |||.........:..:.:||||||..:....|.:.|.|||..|..
Mouse     7 SEPAGSMDASAEQSL-----PEPGSQDSVAGEDIEIVVNVGGVRQVLYGDLLSQYPETRLAELIN 66

  Fly   339 CTT--HEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVD 401
            |..  ::.|..|||||.....|::|||.|.:|..::..|..|::|:...:|.:.|.:::::|.||
Mouse    67 CLAGGYDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVD 131

  Fly   402 ELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARV 466
            ..:|:.||:....:::|.: ||:.:..:.:......:..||:....||.:|:.||||.:|..|||
Mouse   132 LKFLDDCCKSHLSEKREEL-EEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARV 195

  Fly   467 IAVISILFIVLSTIALTLNTLPQLQHIDN-GTPQDNPQLAMVEAVCITWFTLEYILRFSASPDKW 530
            :||:|.|.|::|::.:.:.|:|:||.:|: |...::|.|..||..||.||||||:||..:||:|.
Mouse   196 VAVLSFLLILVSSVVMCMGTIPELQVVDSEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKL 260

  Fly   531 KFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQS 595
            .|....:||:|:|||||::|||.|........ :..:|::.||..|||||.||.||||||:|||:
Mouse   261 HFALSFMNIVDVLAILPFYVSLTLTHLGARMM-ELTNVQQAVQALRIMRIARIFKLARHSSGLQT 324

  Fly   596 LGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIY 660
            |.:.|:.|:||||||:::||:|:.:||:|.|..|:...:|.|.|||::||||.||||||||||||
Mouse   325 LTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIY 389

  Fly   661 PTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRR---EALDRAKREG 719
            |.|.|||:...:..:|||:.|||||..|:|||..:|..|...|.|.|..   ..|:.:..||
Mouse   390 PKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELNSSSAEG 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	36/108 (33%)
		BTB_2	309..408	CDD:280393	34/100 (34%)
		Ion_trans	501..700	CDD:278921	105/198 (53%)
		Ion_trans_2	613..696	CDD:285168	46/82 (56%)
Kcnf1	NP_963289.2	BTB_POZ_Kv5_KCNF1	35..150	CDD:349690	37/114 (32%)
		Ion_trans	193..429	CDD:366146	120/236 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920