| Sequence 1: | NP_001189037.1 | Gene: | Shab / 38352 | FlyBaseID: | FBgn0262593 | Length: | 1607 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000208.2 | Gene: | KCNA1 / 3736 | HGNCID: | 6218 | Length: | 495 | Species: | Homo sapiens |
| Alignment Length: | 468 | Identity: | 171/468 - (36%) |
|---|---|---|---|
| Similarity: | 261/468 - (55%) | Gaps: | 72/468 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 308 RVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSIL 372
Fly 373 NFYRT-GKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDE 436
Fly 437 EEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQ---------- 491
Fly 492 HIDNGTPQDNPQL-----AMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVS 551
Fly 552 L--FLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFL 614
Fly 615 AMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVL 679
Fly 680 VIALPIPIIVNNFAEFYKNQMRREKA----------------LKRREALDRAKRE---------G 719
Fly 720 SIVSFHHINLKDA 732 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Shab | NP_001189037.1 | BTB | 309..416 | CDD:197585 | 31/107 (29%) |
| BTB_2 | 309..408 | CDD:280393 | 30/99 (30%) | ||
| Ion_trans | 501..700 | CDD:278921 | 100/205 (49%) | ||
| Ion_trans_2 | 613..696 | CDD:285168 | 48/82 (59%) | ||
| KCNA1 | NP_000208.2 | Tetramerization domain. /evidence=ECO:0000250|UniProtKB:P10499 | 1..128 | 30/98 (31%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..30 | ||||
| BTB_2 | 39..130 | CDD:308049 | 30/104 (29%) | ||
| Ion_trans | 166..418 | CDD:306908 | 117/251 (47%) | ||
| S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142 | 310..323 | 7/12 (58%) | |||
| Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142 | 372..377 | 4/4 (100%) | |||
| PDZ-binding. /evidence=ECO:0000250 | 493..495 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||