Protein Alignment Shab and Kcna7

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001102384.1
• Gene: Kcna7 / 365241
• RGDID: 1309632
• Length: 489
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 177/494 - (35%)
• Similarity: 249/494 - (50%)
• Gaps: 106/494 - (21%)

  Fly   255 GVGGASSQSISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHE 319
            ||..||.        .|.:|....|::....|    .|||        .....|:.:||.|:|.|
  Rat    13 GVAAASG--------PHVRSPVARAVRAMEPR----CPPP--------CGCCERLVLNVAGLRFE 57

  Fly   320 VLWRTLERLPHTRLG----RLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRT-GK 379
            ...|||.|.|.|.||    |.|             .|..|..|||||||..||.::|.:|:: |:
  Rat    58 TRARTLGRFPDTLLGDPVRRSR-------------FYDGARREYFFDRHRPSFDAVLYYYQSGGR 109

  Fly   380 LHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKC 444
            |.....:.:..|.:::.::|:.                          |.:|.:..|:|    .|
  Rat   110 LRRPAHVPLDVFLEEVSFYGLG--------------------------AAALARLREDE----GC 144

  Fly   445 A----------EYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQ---------- 489
            |          .:.:.||.|.|.|.:|.||||:||:|:|.|::|.:...|.|||.
  Rat   145 AVPPERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRDDRDDPGL 209

  Fly   490 ----------LQHIDNGTPQD--------NPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGG 536
                      |..::..:|..        |....:||.:||.||:.|.::|.:|.|.|..|||..
  Rat   210 APVAAATGSFLARLNGSSPMPGAPSRQPFNDPFFVVETLCICWFSFELLVRLAACPSKAVFFKNV 274

  Fly   537 LNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLR 601
            :|:||.:|||||||:|......:....|......:::|.|::|:.||.||:|||.|||.||.|||
  Rat   275 MNLIDFVAILPYFVALGTELARQRGVGQPAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLR 339

  Fly   602 NSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALG 666
            .|.:|||||:.||.:||::|||..||||.|..||.|.||||:||||.:|||||||||:.|.|..|
  Rat   340 ASMRELGLLIFFLFIGVVLFSSAVYFAEVDRADTHFTSIPESFWWAVVTMTTVGYGDMAPVTVGG 404

  Fly   667 KVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKA 705
            |::|::|.|.|||.|:||:|:||:||:.||..:...|:|
  Rat   405 KIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEA 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	33/112 (29%)
		Ion_trans	464..700	CDD:459842	118/263 (45%)
Kcna7	NP_001102384.1	BTB_POZ_KCNA7	47..154	CDD:349715	38/149 (26%)
		Ion_trans	233..437	CDD:459842	103/203 (51%)