Protein Alignment Shab and Sh

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_728123.1
• Gene: Sh / 32780
• FlyBaseID: FBgn0003380
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 915
• Identity: 241/915 - (26%)
• Similarity: 365/915 - (39%)
• Gaps: 327/915 - (35%)

  Fly    52 QQQQHSKQQQQQQQQQQQQLQLKQHQQQQQDILYQQHNEAIAIARGLQAATPADIGDNQPYYDTS 116
            :.:||.|:||||||.|::||:.|:.|::..:...|...:.:                      ..
  Fly    12 EDRQHRKKQQQQQQHQKEQLEQKEEQKKIAERKLQLREQQL----------------------QR 54

  Fly   117 GNVDWERAMGAGGAGAYGGIGIGSLPAAGGAAYHLGPANPAGLVSRHLDYGDGGHLAGPSAGLPA 181
            .::|                |.||||       .|...:..|
  Fly    55 NSLD----------------GYGSLP-------KLSSQDEEG----------------------- 73

  Fly   182 GAVGSGAGAGAGAGASVTGSGSGAGTGTGTGAGSGSGSGAAGKEVRYAPFPVASPTHSIPTTSQQ 246
                                          |||.|.|.|               |.|..|
  Fly    74 ------------------------------GAGHGFGGG---------------PQHFEP----- 88

  Fly   247 IVGSVGGVGVGGASSQSISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSI 311
                                                        ||....|.        .||.|
  Fly    89 --------------------------------------------IPHDHDFC--------ERVVI 101

  Fly   312 NVGGVRHEVLWRTLERLPHTRLG----RLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSIL 372
            ||.|:|.|...|||.:.|.|.||    |||.             :....|||||||...||.:||
  Fly   102 NVSGLRFETQLRTLNQFPDTLLGDPARRLRY-------------FDPLRNEYFFDRSRPSFDAIL 153

  Fly   373 NFYRT-GKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDE 436
            .:|:: |:|.....:.:..||::::::.:.:..:     :|:.:.:..:.||.|...::
  Fly   154 YYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAI-----NKFREDEGFIKEEERPLPDN------ 207

  Fly   437 EEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQH------IDN 495
                     |.|:.:|.|.|.|.:|.||||:|:||:..|:||.:...|.|||:.:|      ..|
  Fly   208 ---------EKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTN 263

  Fly   496 GT-------PQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLF 553
            ||       |.......::|.:||.|||.|..:||.|.|:|..|.:..:|:||::||:|||::|.
  Fly   264 GTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLA 328

  Fly   554 LLETNKNATDQF-------QDVR-------RVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSY 604
            .:...:..|...       ||..       .:::|.|::|:.||.||:|||.|||.||.||:.|.
  Fly   329 TVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASM 393

  Fly   605 KELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVI 669
            :|||||:.||.:||::|||..||||...:::.|.|||:.||||.:|||||||||:.|....||::
  Fly   394 RELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIV 458

  Fly   670 GTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREALDRAKREGSIVSFHHI------- 727
            |::|.|.|||.||||:|:||:||..||..:..:|:...:              :|:|:
  Fly   459 GSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQ--------------NFNHVTSCPYLP 509

  Fly   728 ----------NLKDAFAKSMDLIDVIVDTGKQTNVVHPKGKRQSTPNIGRQTLDVQSAPGHNLSQ 782
                      :|.::.:..|||.|.:..|...|. .|| |:....|.:|.|  ..|..|
  Fly   510 GTLGQHMKKSSLSESSSDMMDLDDGVESTPGLTE-THP-GRSAVAPFLGAQ--QQQQQP------ 564

  Fly   783 TDGNSTEGESTSGRNPATTGTGCYKNYDHVANLRNSNLHNRRGSSSEQDAVPPYSFDNPNARQTS 847
                                         ||:..:.::..:.....:|            ..||.
  Fly   565 -----------------------------VASSLSMSIDKQLQHPLQQ------------LTQTQ 588

  Fly   848 MMAMESYRREQQALLQQQ----QQQQQQMLQMQQIQQKAPNGN-GGATGGGVANNLAMVAASSAA 907
            :     |:::||...|||    |||||...|:||.|....|.: ..||.|..::.|.|...::.|
  Fly   589 L-----YQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALA 648

  Fly   908 TAVAT 912
            .::.|
  Fly   649 VSIET 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	35/112 (31%)
		Ion_trans	464..700	CDD:459842	114/262 (44%)
Sh	NP_728123.1	BTB_POZ	97..223	CDD:453885	44/158 (28%)
		Ion_trans	226..488	CDD:459842	114/261 (44%)